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Flashcards in GI drugs Deck (9)
1

What are the 2 pathways for ZE syndrome to cause increase acid production?

Stimulate gastrin and histamine receptor

2

Are H2 blockers competitive or noncompetitive?

Competitive

3

What drug is most effective against ZE syndrome?

PPI

4

Why can't you take sucralfate with other antacid drugs?

Because it needs an acidic environment to work

5

What anti acid drugs have the fastest onset?

Antacid (Aluminum/Mg/Ca)

6

What are the 2 receptors in chemoreceptor trigger zone? what other 2 receptors stimulate vomiting?

5HT3 and D2
M1 and NK-1

7

Which receptor when stimulated, has antiemetic effect?

CB1 (weed)

8

What are the 2 D antagonists drugs that are antiemetic? and what are their side effects?

Prochlorperazine/metochlopramide (also promotility)/movement disorders (pseudo parkinson)

9

H1 or H2 blockers have antiemetic effect? example?

H1 (promethazine)