Glia 1

Question 1

Four types of glia?

Answer 1

Astrocyte, microglia, oligodendroglia, schwann cell

Question 2

Roles of oligodendrocytes and schwann cells?

Answer 2

Myelinate the neurones

Question 3

Location of oligodendrocytes?

Answer 3

Brain, SC (CNS)

Question 4

Location of schwann cells?

Answer 4

PNS

Question 5

WHat are neural cells?

Answer 5

Neurons or glia

Question 6

Two subtypes of glia?

Answer 6

Macroglia and microglia

Question 7

Four types of macroglia?

Answer 7

Astrocytes, radial glia, oligodendroglia, schwann cells

Question 8

Role of myelinating glia?

Answer 8

Encase the axon with a myelin sheath

Question 9

Role of myelin sheath?

Answer 9

Insulates axons and speeds up the rate of nerve conduction of AP along axons

Question 10

Roles of radial glia?

Answer 10

Provide scaffolding during nervous system development, pathways for migrating cells
Produce matrix and adhesion proteins

Question 11

Why are radial glia no longer needed into adulthood?

Answer 11

No more neuronal migration is occurring

Question 12

Radial glia role in adults?

Answer 12

Persits in cerebellum (Bergmann glia) and retina (Muller cells)

Question 13

Role of cerebral spinal fluid?

Answer 13

brain health, allows movement of various molecules

Question 14

Where are ependymal cells found?

Answer 14

Lining walls of fluid filled ventricles in the brain

Question 15

Functional component of ependymal cells?

Answer 15

Beating cilia that allows movement of cerebral spinal fluid over the brain and SC

Question 16

Embryonic origin of neurons, astrocytes and oligodendrocytes?

Answer 16

Neural tube

Question 17

Embryonic origin of schwann cells?

Answer 17

Neural crese

Question 18

Origin of microglia?

Answer 18

Derived from macrophages (blood)

Question 19

Embryonic origin of microglia?

Answer 19

Blood cells that develop in the placental yolk region

Question 20

Which two cell types can neuroepithelial stem cells develop into?

Answer 20

Neurons or glial-restricted precursors

Question 21

Which cell types can glial-restricted precursors differentiate into?

Answer 21

Astrocyte precursor cells or O2A progenitors

Question 22

Which cell types can O2A progenitors differentiate into?

Answer 22

Oligodendrocytes or type 2 astrocytes

Question 23

Which cell type does astrocyte precursor cell differentiate into?

Answer 23

Type 1 astrocytes

Question 24

Which type of astrocyte is mainly found in the brain?

Answer 24

Type 1

Question 25

Which cell type that was made in culture has not been identified in the brain?

Answer 25

Type 2 astrocytes

Question 26

Role of projections coming out of astrocytes?

Answer 26

Make contact with other cells in the environment

Question 27

Role of projections coming out of oligodendrocytes?

Answer 27

Wrap around axons to make the myelin sheath

Question 28

Where, embryonically, do the majority of microglia come from?

Answer 28

Placental yolk

Question 29

What happens to microglia in development after being generated by macrophages?

Answer 29

They migrate to the brain

Question 30

Other, smaller, way of microglia entering the brian?

Answer 30

Cells generated in the bone marrow go to the blood, then enter the brain, then become microglia