GLOSSARY SECTION I PART A Flashcards
Chance that each child has of getting a disease if only one parent is affected
Reduction in normal gene product associated with clinical symptoms
Reduction in enzyme Activity that can usually be compensated for AR
patients with a DVT that are Asymptomatic
what is the percent?
50%
When more than ___ of the pulmonary circulation is obstructed, Sudden death, Right Heart Failure, Or Cardiovascular Collapse occurs
___ of Pulmonary embolisms are Silent Pulmonary embolisms
60%
___ of systemic thromboembolism end up in the lower extremity
___ of people who acquire HIV/AIDs get it from sexual contact
75%
Most cancers occur after 55 years old
age
C3a and C5a from the complement system
Induce degranulation of mast cells and basophils
Anaphylatoxins
Causes shock – severity reflects level of sensitivity
Causes pruritus, urticarial, erythema, bronchoconstriction, laryngeal edema, bronchial obstruction
Systemic Anaphylaxis
Caused by inhaled or ingested administration of allergen
Contact dermatitis, diarrhea, bronchoconstriction, hives, asthma
Local Anaphylaxis
Leakage from new blood vessels
This is why diabetics have a lot of swelling
Angiogenesis
A protein produced in response to and counteracting a specific antigen
Combine chemically with substances in the body and recognizes them as alien
Antibodies
Potent inhibitor of the coagulation cascade (if deficient then too much clotting)
Antithrombin III
Internally controlled programmed cell death – minimal effect to surrounding tissue
Eliminates unwanted host cells in certain situations: embyogenesis, hormone-dependent physiologic involution (after pregnancy), over-proliferating cell population, autoreactive T-cells in thymus, disease, tumor, atrophy
Involves activation of capases (via mitochondrial pathway or death receptor pathway)
Apoptosis
Type III hypersensitivity
Ag injected into skin and Ab-Ag complex forms in skin leading to vasculitis and necrosis
4-10 days
Arthus Reaction
Genetic predisposition to develop reactions to inhaled or ingested antigens
Atopy
Shrinkage in the size and function of cells resulting in decrease in organ size
Causes: no nerve or blood supply, malnutrition, low hormones
Decreased protein synthesis + increased protein degredation
Atrophy
Acting on self
Autocrine
