Gout- NSAIDs DI

Question 1

NSAIDs with indications for gout treatment

Answer 1

Indomethacin, naproxen, sulindac

Question 2

NSAID MoA

Answer 2

COX inhibition

Question 3

When to administer an NSAID in a gout flare

Answer 3

<24 hours, doesn’t matter what NSAID it is

Question 4

Avoid NSAIDs in what disease states/complications?

Answer 4

Renal insufficiency/failure
Bleeding disorders/anticoagulated patients
PUD
CHF
Adults >=75

Question 5

Resolution of gout symptoms with NSAIDs

Answer 5

Usually within 5-7 days, but treatment may extend beyond that