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pharm > GOUT/RA > Flashcards

GOUT/RA Flashcards

1
Q

Antimalarials/hydroxychloroquine

A

antiparasitic drug, dunno how it works for RA lol.

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2
Q

Pencillamine

A

metal chelator, inhibits macrophages, il-1, t cell proliferation

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3
Q

Colchicine

A

blocking chemotaxis

GI issues with high dose DIARRHEAAAAA

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4
Q

allopurinol

A

Inhibits xanthine oxidase which decreases production of uric acid

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5
Q

/ Probenecid, sulfinpyrazone

A

decreases uric acid by decreasing uric acid reabsorption, MOA inhibits OAT1-3 and URAT to decrease reabs in prox renal tubule.

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6
Q

pegloticase

A

uric acid to allantoin,infusion reactions

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7
Q

Fubuxostat, non prune XOI

A

blocks uric acid production

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pharm (24 decks)

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