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Microbiology > Gram positive bacilli > Flashcards

Gram positive bacilli Flashcards

1
Q

Bacillus anthracis common symptoms

A
  1. Eschar
    2.
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2
Q

Bacillus anthracis description

A

Large rods in chains

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3
Q

Bacillus anthracis capsule

A

Made of protein

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4
Q

Bacillus anthracis use of oxygen

A

Obligate aerobe

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5
Q

Does Bacillus anthracis have spores

A

YESSSSSSSSSSS

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6
Q

Bacillus anthracis toxins

A
  1. Edema factor
  2. Lethal factor
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7
Q

Edema factor in Bacillus anthracis

A

Functions as an adenylate cyclase

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8
Q

Lethal factor in Bacillus anthracis

A

Endotoxin that acts as a protease of MAP kinase
Causes tissue necrosis in a host cell

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9
Q

Wool sorters disease

A

Pulmonary anthrax

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10
Q

Pulmonary anthrax complications

A

Pulmonary hemorrhage (almost 100% mortality)
Widened mediastinum

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11
Q

Bacillus anthracis treatment

A

Fluroquinolones
Doxycycline

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12
Q

Bacillus cereus facts

A

Spore forming and aerobic

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13
Q

Bacillus cereus manifestations

A

Food poisoning from reheating rice

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14
Q

Clostridium tetani and oxygen

A

Obligate anaerobe

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15
Q

Clostridium tetani and spores

A

Spore forming

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16
Q

Where is Clostridium tetani found

A

Soil

17
Q

How does the Clostridium tetani enter the body

A

Cuts by rusty nails or soil

18
Q

Clostridium tetani symptoms

A

Spastic paralysis
Evil smile
Lock jaw
Opisthions- extension and arching of the back

19
Q

Clostridium tetani pathogenesis

A
  1. Puncture wound
  2. Bacterium vegetates
  3. Produces tetanus toxin
  4. Toxin travels retrograde through spinal cord (motor neurons)
  5. Toxin acts as a protease
  6. Protease cuts SNARE proteins
  7. Without SNARE, GABA and glycine are inhibited
20
Q

Renshaw cells

A

Sense activity of nearby neurons

21
Q

Clostridium tetani vaccine

A

Toxoid vaccine- toxin conjugated to a protein to increase immunogenicity

Microbiology (5 decks)

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