Gram Positive Rods Flashcards Preview

Microbiology > Gram Positive Rods > Flashcards

Flashcards in Gram Positive Rods Deck (45):
0

Aerobic, non motile
Box car shaped/Medusa head

Bacillus anthracis

1

Aerobic non motile, reheated fried rice/Chinese fried rice

Bacillus cereus

2

Anaerobic, tennis racket like/lollipop like causing spastic paralysis

Clostridium tetani

3

Anaerobic, bulging cans causing flaccid paralysis

Clostridium tetani

4

Anaerobic, lecithinase gas forming

Clostridium perfringens

5

Anaerobic causing pseudomembranes and antibiotic associated diarrhea

Clostridium defficile

6

Aerobic, non motile, curved, chinese character

Corynebacterium diphtheriae

7

Bacteria causing pseudomembranous pharyngitis

Corynebacterium diphtheria

8

Aerobic, curved, tumbling motility with actin rockets

Listeria monocytogenes

9

Spore forming gram positive rods

Clostridium
Bacillus

10

Inhalation of spore from animal hair and wool

Woolsorters disease
B anthracis

11

Dry gound glass surface and irregular edges with projections along lines of inoculation

Medusa head morphology
B anthracis

12

DOC for Anthrax

Ciprofloxacin

13

MCC of death in Anthrax

Pulmonarry hemorrhage

14

Diseases with Pulmonary hemorrhage as their cause of death

Inhalational Anthrax
Congenital Syphilis
Weils syndrome
I Ate Cake SWeet

15

A protease that cleaves proteins involved in the release of glycine from Renshaw cells in spinal cord

Tetanospasmin (Tetanus toxin)

16

DOC for C tetani

Metronidazole

17

A drug that inhibits glycine activity hence should not be used in C tetani

Penicillin

18

This blocks acetylcholine release causing flaccid paralysis (descending pattern)

Botulinum toxin

19

Triad of Botulism

Symmetric descending flaccid paralysis with prominent bulbar involvement (bulbar signs-diplopia, dysphonia, dysarthria, dysphagia)
Absence of fever
Intact sensorium

20

Infant botulism

Floppy baby syndrome

21

In infant botulism, theres absence of

Competitive bowel microbes

22

Double hemolysis on blood agar

Clostridium perfringens

23

A lecithinase that cleaves cell membrane

Alpha toxin
C perfringens causing gas gangrene

24

DOC for gas gangrene

Penicillin

25

Antibiotics that cause C defficile associated diarrhea

Clindamycin
1st and 2nd Gen Cephalosporins
Ampicillin

26

Sequelae of Pseudomembranous colitis

Toxic megacolon

27

What causes Pseudomembranous pharyngitis?

Corynebacterium diphtheriae

28

What causes Pseudomembranous esophagitis?

Candida albicans

29

What causes Pseudomembranous colitis?

Clostridum defficile

30

DOC for C defficile

Metronidazole
Vancomycin - poor oral bioavailability - stays at GI

31

Club or comma shaped rods arranged in V ir L shape looks like a Chinese Character

Corynebacterium diphtheriae

32

The toxigenicity of Corynebacterium diphtheriae is detected using

Modified Elek test

33

Granules seen in Corynebacterium diphtheriae

Metachromatic granules/ Babes Ernst/ Volutin

34

Pathogenesis of Diphteria

ADP ribosylation - exotoxin
Beta prophage - encoded the exotoxin - transduction - lysogenized
Corynebacterium
Diphtheriae
Elongation factor 2 - for translation
Granules - metachromatic/ babes ernst/ volutin

35

Beta prophage encoded toxins

ShigA like yoxin in EHEC
Botulinum toxin
Cholera toxin
Diphtheria toxin
Erythrogenic toxin in S pyogenes - Scarlet fever

36

This results from death of mucosal epithelial cells

Psedomembrane

37

Treatment for Corynebacterium diphtheriae

Antitoxin and Pen G

38

Cold enhancement - paradoxical growth in cold temperature

Listeria monocytogenes

39

Tumbling motility

Listeria monocytogenes

40

Narrow zone of beta hemolysis

Listeria monocytogenes

41

Ingestion of unpasteurized milk

Listeria monocytogenes (also get TB)

42

This propels Listeria monocytogenes through the membrane of one human cell to another

Actin rockets

43

Escape from phagosomes

Listeriolysin
Listeria monocytogenes

44

DOC for Listeriosis

Ampicillin with or without Gentamicin