Group 3 and 4

Question 1

What family does Rotavirus belong to?
A. Picornaviridae
B. Reoviridae
C. Caliciviridae
D. Flaviviridae

Answer 1

B. Reoviridae

Question 2

Which virus is the most common cause of infantile gastroenteritis?
A. Poliovirus
B. Echovirus
C. Rotavirus
D. Norovirus

Answer 2

C. Rotavirus

Question 3

What is the main transmission route of Rotavirus?
A. Respiratory
B. Sexual contact
C. Fecal-oral
D. Bloodborne

Answer 3

C. Fecal-oral

Question 4

Which protein of Rotavirus acts as an enterotoxin?
A. VP1
B. NS4
C. VP6
D. NS2

Answer 4

B. NS4

Question 5

What is a diagnostic test for Rotavirus?
A. Gram stain
B. ELISA
C. Ziehl-Neelsen
D. VDRL

Answer 5

B. ELISA

Question 6

What virus causes Colorado Tick Fever?
A. Norovirus
B. Coltivirus
C. Dengue virus
D. Hepatitis E

Answer 6

B. Coltivirus

Question 7

What is the vector of Coltivirus?
A. Aedes aegypti
B. Culex
C. Dermacentor andersoni
D. Anopheles

Answer 7

C. Dermacentor andersoni

Question 8

What does “Pico” in Picornavirus mean?
A. Big
B. Heat
C. RNA
D. Small

Answer 8

D. Small

Question 9

Which virus is included in the genus Hepatovirus?
A. HAV
B. HEV
C. HCV
D. HDV

Answer 9

A. HAV

Question 10

Which virus uses CD155 as a receptor?
A. Rotavirus
B. Poliovirus
C. Dengue virus
D. Coronavirus

Answer 10

B. Poliovirus

Question 11

What disease is caused by Coxsackievirus A16?
A. Dengue
B. HFMD
C. Hepatitis
D. AIDS

Answer 11

B. HFMD

Question 12

What type of genome do Picornaviruses have?
A. dsDNA
B. ssDNA
C. ssRNA
D. dsRNA

Answer 12

C. ssRNA

Question 13

What is the most common cause of adult gastroenteritis in the U.S.?
A. Rotavirus
B. Norovirus
C. HEV
D. HAV

Answer 13

B. Norovirus

Question 14

Which virus is transmitted by Aedes mosquitoes and causes “Breakbone Fever”?
A. Yellow Fever Virus
B. Dengue Virus
C. Chikungunya
D. West Nile Virus

Answer 14

B. Dengue Virus

Question 15

What protein causes endothelial damage in Dengue?
A. E1
B. NS1
C. VP6
D. CD155

Answer 15

B. NS1

Question 16

Which virus has a high mortality rate and is transmitted via Culex mosquitoes?
A. WNV
B. Yellow Fever
C. St. Louise Encephalitis Virus
D. Zika Virus

Answer 16

C. St. Louise Encephalitis Virus

Question 17

Which virus is not enveloped?
A. Coronavirus
B. Picornavirus
C. Flavivirus
D. Rubella

Answer 17

B. Picornavirus

Question 19

What virus causes German measles?
A. Rubeola
B. Rubella
C. Roseola
D. Rotavirus

Answer 19

B. Rubella

Question 20

Which virus has club-shaped projections?
A. Rubella
B. Coronavirus
C. Dengue
D. WNV

Answer 20

B. Coronavirus

Question 21

What virus is linked to “Councilman bodies”?
A. HCV
B. Dengue
C. Yellow Fever
D. HEV

Answer 21

C. Yellow Fever

Question 22

What is the mode of transmission of HAV?
A. Bloodborne
B. Sexual
C. Fecal-oral
D. Airborne

Answer 22

C. Fecal-oral

Question 23

What diagnostic marker is used for acute HAV infection?
A. HBsAg
B. Anti-HAV IgM
C. Anti-HBc
D. Anti-HCV

Answer 23

B. Anti-HAV IgM

Question 24

What virus requires HBV for replication?
A. HAV
B. HEV
C. HDV
D. HCV

Answer 24

C. HDV

Question 25

Which virus has an oral live vaccine by Albert Sabin? A. Rotavirus B. Norovirus C. Poliovirus D. Yellow fever

Answer 25

C. Poliovirus

Question 26

What genus does the Japanese Encephalitis virus belong to? A. Flavivirus B. Rubivirus C. Hepacivirus D. Togavirus

Answer 26

A. Flavivirus

Question 27

What mosquito is the main vector for Zika virus? A. Aedes B. Anopheles C. Culex D. Ixodes

Answer 27

A. Aedes

Question 28

Which virus is not enveloped? A. Coronavirus B. Picornavirus C. Flavivirus D. Rubella

Answer 28

B. Picornavirus

Question 29

Which of the following causes congenital rubella syndrome? A. Rubella virus B. Coronavirus C. Dengue virus D. HSV

Answer 29

A. Rubella virus

Question 30

What virus is associated with Guillain-Barré Syndrome? A. HFMD B. Zika virus C. HEV D. HAV

Answer 30

B. Zika virus

Question 31

What is the vector for Yellow Fever in the urban cycle? A. Anopheles mosquito B. Aedes aegypti C. Culex mosquito D. Tsetse fly

Answer 31

B. Aedes aegypti

Question 32

What are Councilman bodies indicative of? A. Hepatic necrosis B. Viral exanthema C. CNS damage D. Gastrointestinal damage

Answer 32

A. Hepatic necrosis

Question 33

What is the most common vector for West Nile Virus? A. Aedes B. Anopheles C. Culex D. Dermacentor

Answer 33

C. Culex

Question 34

What is the incubation period of Hepatitis A? A. 3–5 days B. 1 week C. 4–6 weeks D. 1–2 months

Answer 34

C. 4–6 weeks

Question 35

Which hepatitis virus is most dangerous in pregnancy? A. HAV B. HBV C. HCV D. HEV

Answer 35

D. HEV

Question 36

What test confirms West Nile virus? A. Gram stain B. ELISA C. RT-PCR D. Widal

Answer 36

C. RT-PCR

Question 37

What is the structural shape of most positive-sense RNA viruses? A. Helical B. Complex C. Icosahedral D. Circular

Answer 37

C. Icosahedral

Question 38

Which virus causes rash but spares palms and soles? A. Rubella B. HFMD C. Dengue D. EEE virus

Answer 38

A. Rubella

Question 39

What family does Hepatitis C virus belong to? A. Hepadnaviridae B. Caliciviridae C. Flaviviridae D. Picornaviridae

Answer 39

C. Flaviviridae

Question 40

The vector of Eastern Equine Encephalitis virus is: A. Aedes B. Anopheles C. Culex spp D. Ixodes

Answer 40

C. Culex spp

Question 41

What is the key laboratory sign of Dengue Hemorrhagic Fever (DHF)? A. Leukocytosis B. Thrombocytopenia C. Hyperkalemia D. Neutropenia

Answer 41

B. Thrombocytopenia

Question 42

What is the genome type of Reoviridae? A. ssRNA B. dsDNA C. ssDNA D. dsRNA

Answer 42

D. dsRNA

Question 43

What virus can cause herpangina? A. Norovirus B. Coxsackie A C. Dengue D. Rubella

Answer 43

B. Coxsackie A

Question 44

What is the transmission of HEV? A. Bloodborne B. Sexual C. Fecal-oral D. Airborne

Answer 44

C. Fecal-oral

Question 45

Which virus replicates in epithelial cells of the microvilli? A. Norovirus B. Rotavirus C. HFMD virus D. Coronavirus

Answer 45

B. Rotavirus

Question 46

What does the “Orphan” in REO virus stand for? A. Animal origin B. No known disease at first C. First found in children D. Non-viral structure

Answer 46

B. No known disease at first

Question 47

What type of vaccine is RotaTeq? A. Injected live attenuated B. Oral killed C. Oral live D. Nasal inactivated

Answer 47

C. Oral live

Question 48

What type of illness does Norovirus typically cause? A. Hepatitis B. Encephalitis C. Gastroenteritis D. Pneumonia

Answer 48

C. Gastroenteritis

Question 49

What is the most common genus in Togaviridae that causes encephalitis? A. Rubivirus B. Hepacivirus C. Alphavirus D. Lentivirus

Answer 49

C. Alphavirus

Question 50

Which hepatitis virus is bloodborne? A. HAV B. HBV C. HEV D. None

Answer 50

B. HBV

Question 51

What distinguishes HAV from HBV? A. HBV is fecal-oral B. HAV causes chronic disease C. HAV is self-limiting and fecal-oral D. HBV doesn’t affect the liver

Answer 51

C

Question 52

What is the natural reservoir for Yellow Fever in sylvatic cycle? A. Humans B. Monkeys C. Bats D. Pigs

Answer 52

B. Monkeys

Question 53

What distinguishes HBV from HCV? A. HBV is RNA virus B. HCV has a vaccine C. HBV has surface and core antigens D. HCV infects only children

Answer 53

C

Question 54

What virus causes encephalitis and has birds as a reservoir? A. HFMD virus B. EEE virus C. HAV D. Dengue

Answer 54

B. EEE virus

Question 55

Which virus is linked with Guillain-Barré Syndrome? A. Rotavirus B. Zika C. HAV D. Polio

Answer 55

B. Zika

Question 56

Which hepatitis virus is a hepadnavirus? A. HBV B. HAV C. HCV D. HEV

Answer 56

A. HBV

Question 57

What distinguishes Rubella rash? A. Vesicular rash B. Rash spreads from trunk to face C. Rash with no palms/soles involvement D. Always involves palms

Answer 57

C

Question 59

What virus causes German measles? A. Rubeola B. Rubella C. Roseola D. Rotavirus

Answer 59

B. Rubella

Question 60

Which virus has club-shaped projections? A. Rubella B. Coronavirus C. Dengue D. WNV

Answer 60

B. Coronavirus

Question 61

What receptor does SARS-CoV-2 target? A. CCR5 B. CD4 C. ACE2 D. CD155

Answer 61

C. ACE2

Question 62

What virus is linked to “Councilman bodies”? A. HCV B. Dengue C. Yellow Fever D. HEV

Answer 62

C. Yellow Fever

Question 63

What is the mode of transmission of HAV? A. Bloodborne B. Sexual C. Fecal-oral D. Airborne

Answer 63

C. Fecal-oral

Question 64

What diagnostic marker is used for acute HAV infection? A. HBsAg B. Anti-HAV IgM C. Anti-HBc D. Anti-HCV

Answer 64

B. Anti-HAV IgM

Question 65

What virus requires HBV for replication? A. HAV B. HEV C. HDV D. HCV

Answer 65

C. HDV

Question 66

Which virus has an oral live vaccine by Albert Sabin? A. Rotavirus B. Norovirus C. Poliovirus D. Yellow fever

Answer 66

C. Poliovirus

Question 67

What genus does the Japanese Encephalitis virus belong to? A. Flavivirus B. Rubivirus C. Hepacivirus D. Togavirus

Answer 67

A. Flavivirus

Question 68

What mosquito is the main vector for Zika virus? A. Aedes B. Anopheles C. Culex D. Ixodes

Answer 68

A. Aedes