Growth Adaptations, Cell Injury/death Flashcards Preview

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Flashcards in Growth Adaptations, Cell Injury/death Deck (16):
1

Increase in Cell size

hypertrophy

2

Increase in cell #

hyperplasia

3

Hypertrophy requires

gene activation
protein synth
organelle production

4

Tissues that can only undergo hypertrophy--permanent tissues

Cardiac
sk. mm
Nerves

5

Hyperplasia that does not progress to dysplasia

BPH

6

Decrease in stress --> decrease in organ size

atrophy

7

Ubiquitin proteosome degradation

cytoskeleton marked with ubiquitin and destroyed

cell decreases in size --> atrophy

8

Atrophy mechanism that decreases cell #

apoptosis

9

Change in cell type

Metaplasia

10

Mechanism of Metaplasia

reprogramming of stem cells

reversible

11

Metaplasia with no risk of progression to CA

apocrine metoplasia of the breast

12

Vitamin necessary for differentiation of surface epithelium

Vitamin A

13

Disordered Cellular Growth

Dysplasia

reversible

14

irreversible progression of dysplasia

Carcinoma

15

Failure of cell to be produced during embryogenesis

aplasia

16

Decrease in cell production during embryogenesis

hypoplasia