Growth hormone Flashcards
1
Q
Secreted by
A
Anterior pit
2
Q
Stimulates
A
1) Linear growth and muscle mass
via IGF-1 (liver)/somatomedin (liver) secretion
2) increase insulin resistance (diabetogenic)
3
Q
Regulation
A
Released in pulses in response to GHRH
Stimulate by exercise and sleep
Inhibited by glucose and somatostatin
4
Q
Excess GH
A
(by pituitary adenoma)
Acromagaly in adults
Gigantism in children
