GU Flashcards

1
Q

What is the function of the kidneys

A

-function to regulate the body’s electrolytes and fluids which effects BP

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2
Q

What hormones affect H20 Reabsorption

A

ADH and Aldosterone

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3
Q

What is considered average urine output?

A

1,500mL/day

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4
Q

What is the definition of oliguria

A

<400ml/day

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5
Q

What is normal values for creatinine

A

Males 0.7-1.3mg/dL

Females 0.6-1.1mg/dL

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6
Q

What affects creatinine levels

A
  • gender (males)
  • race (Black people have more muscle mass)
  • Muscle mass
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7
Q

What does the creatinine clearance (24 hour urine) evaluate

A

Microalbuminuria, albuminuria, proteinuria

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8
Q

What is the best test of kidney function

A

eGFR

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9
Q

How is the eGFR calculated

A

creatinine, age and gender

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10
Q

What makes an eGFR less reliable

A
  • pregnancy
  • muscle wasting
  • elderly
  • lower extremity amputee
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11
Q

What is a normal eGFR

A

> 90mL/min

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12
Q

What is CKD Stage 1

A

> 90mL/min; damage but normal function

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13
Q

What is CKD Stage 2

A

60-89mL/min

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14
Q

What is CKD Stage 3a

A

45-59mL/min

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15
Q

What is CKD Stage 3b

A

30-44mL/min

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16
Q

What is CKD Stage 4

A

15-30mL/min

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17
Q

What is CKD Stage 5

A

<15mL/min

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18
Q

What is BUN

A

measurement of the kidney’s ability to excrete urea (which is a waste product of protein metabolism)

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19
Q

What are causes of increased BUN

A
  • AKI
  • High protein diet
  • Hemolysis
  • CHF
  • Drugs
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20
Q

What are causes of decreased BUN

A

liver damage or disease

21
Q

What is the BUN: Creatinine ratio useful for

A

Classifying the type of renal failure

If there is a decreased blood flow to the kidneys then there will be an increased BUN: Creatinine ratio

22
Q

What does proteinuria indicate?

A

Kidney damage

23
Q

What is the most common bacteria to cause a UTI

24
Q

What are sx of a UTI

A
  • Dysuria
  • Urgency
  • Frequency
  • Hematuria
  • Foul-smelling urine
  • Sensation of incomplete emptying, scant voiding
  • Lower abdominal pain
  • Back pain* think pyelo
25
What is the colony count of a midstream urine that indicates a UTI
>100,000 CFU
26
Urine Cultures should be done on:
1. Recurrent or refractory infections 2. Children and pregnant women 3. 65+
27
What is the most reliable indicator of UTI in a UA
WBC
28
What DDx should you consider for frequency and urgency of urine with a normal UA
- Pregnancy - Vaginitis - STI - Herpes - UTI but diluted sample - Overactive sample
29
What antibiotic is recommended for uncomplicated UTI
1) Nitrofurantonin (Macrobid) 100mg BID *Not in 3rd trimester of pregnancy
30
How long should you treat a UTI in: - men - individuals with co-morbid conditions - Complicated UTIs
7-10 days
31
How long should you treat an uncomplicated UTI
-3 days
32
What other medications should you consider in UTIs
-Antispasmodics: Phenazopyridine (Pyridium) or Flavoxate
33
What health promotion should you initiate in UTI
- Hydration - Avoid Carbonation, ETOH and Caffeine - Void after Sex
34
What is a side effect of Phenazopyridine (Pyridium)
Will discolor urine (orange) and stain contact lenses
35
What are causes of hematuria in adults
- Cancer (renal/bladder) - Infection - Stones - Coagulopathy - Glomerular Disease - Hydronephrosis - Polycystic kidney - Trauma - Meds - Exercise
36
Risk factors for Bladder Cancer
- Smoking - Age >40 - Occupational exposure - Chronic cystitis - History of pelvic irradiation - History of analgesic abuse
37
A patient presents with classic symptoms of a kidney stone what lab abnormality is most likely to be present?
-Hematuria
38
What medications can help with passing kidney stones?
- Alpha blockers | - CCB
39
What are risk factors for pyleonephritis
- Untreated or undertreated UTI - Urinary tract abnormalities - Elderly - Fecal Incontinence - Pregnancy
40
What findings may be present in a patient with pyleo
- CVA tenderness - Fever - Pyuria - WBC in urine - Casts
41
What diagnostic studies are indicated in suspected pyelonephritis
- UA (pyuria, hematuria and maybe mild proteinuria) - C&S - CBC (Leukocytosis) - CVA tenderness - ESR
42
What is mgmt of pyelonephritis
-Quinolones: Only oral Abx recommended for outpatient tx
43
What is the significance of WBC cast
-Pyleonephritis
44
What are the types of incontinence
1) Urge- detrusor instability 2) Stress- sphincter incompetence 3) Mixed (most common)
45
What lifestyle changes are indicated in incontinence
- ETOH - Carbonation - Coffee or tea - Citrus - weight loss - regular voiding (but not frequent) - minimize fluids after dinner
46
Overactive Bladder Management
- Anticholinergics - Mirabegron (less S/E) - Estrogen for post-menopausal women - Biofeedback - Pelvic floor PT
47
What is the ODE to anticholinergics
``` Oh this drug it makes me pink, Sometimes I can't think or even blink I cant see I cant pee I cant spit I cant sh*t ```
48
What findings suggest pyleo over UTI
- fever >100.4 - Back/flank pain - CVA tenderness - WBC casts
49
Use of spermicides can ____ risk of UTI
increase