GYNE SE2 menopause Flashcards Preview

Gyne > GYNE SE2 menopause > Flashcards

Flashcards in GYNE SE2 menopause Deck (22):
1

absence of menstrual periods for at least 6 months in a woman over 40

menopause

2

more rapid oocyte depletion and hypoestrogenism starting age 37

perimenopause

3

time between onset of irregular AND permanent cessation of menses

perimenopause

4

premature menopause before age 40

premature ovarian failure

5

hormonal changes in perimenopause

decreased INHIBIN and increased FSH

6

hormonal changes in established menopause

marked reduction in ESTRADIOL (plus dec inhibin and inc FSH too)

7

first symptom of menopause

menstrual irregularities

8

thin lola vs fat lola during menopause - anong difference

thin lola prone to DRYNESS; fat lola prone to hyperplasia and BLEEDING

9

how to diagnose menopause

use signs and symptoms and physical exam

10

treatment for asymptomatic women

NONE

11

2 main indications of hormonal therapy

for symptomatic women AND to prevent osteoporosis and heart disease

12

most effective treatment for vasomotor symptoms

LOW DOSE hormone therapy (ex. 0.3 mg CEE)

13

route for those with liver problems

transdermal (0.25 mg transdermal estradiol)

14

hormonal treatment for vulvovaginal symptoms

HRT including tibolone

15

first line tx for mood disorders

not HRT but anti-depressants

16

explain the "window of opportunity" concept

HT may be cardioprotective if started around the time of menopause and continued long-term

17

risk for ________ (disease) is INCREASED in women on HRT

venous thromboembolism

18

for women over 60 with rish of osteoporosis, must take ___

raloxifene, biphosphonates or strontium ranelate.. AND .8-1g calcium and 800 IU vitamin D

19

differentiate advantages/disadvantages of two types of HRT regimens

CYCLIC has predicatble and controlled bleeding, CONTINUOUS has good compliance but irregular bleeding

20

hormonal therapy for vasomotor sx, sexual well-bein, vulvovaginal symptoms

TIBOLONE 2.5 mg / day

21

non-HT indicated for hot flushes with depression (SNRI class)

desvenlafaxine

22

woman on HRT with persistent irregular BLEEDING --> how to evaluate

(+) ultrasound -> (+) hysteroscopy --> biopsy --> D&C