What is the function of the haematological
system?
Deliver substance for Cellular
Metabolism,
Remove waste,
Defend against Micro-organisms and injury,
maintain acid-base balance
Cellular components Erythrocytes Most abundant cell in the body Responsible for tissue oxygenation Biconcavity and reversible deformity 120-day life cycle
what is the blood made of?
Composition of blood ➢ 90% water and 10% solutes ➢ 5.5L ➢ pH 7.35-7.45 ➢ Plasma • 50–55% of the blood volume • Organic and inorganic elements
What are some plasma proteins?
• Albumins
Carriers and control the plasma oncotic pressure
• Globulins
Carrier proteins and immunoglobulins (antibodies)
• Clotting factors
Mainly Fibrinogen
What are Leucocytes?
Leucocytes (white blood cells)
• Defend the body against infection and remove debris
what are Granulocytes?
Neutrophils
• Phagocytes in early inflammation
• Granulocytes
Membrane-bound granules in their cytoplasm
Granules contain enzymes capable of destroying microorganisms
Inflammatory and immune functions
Capable of amoeboid movement (diapedesis)
what are Eosinophils
what are Basophils
Structurally and functionally similar to mast cells
• Cytoplasmic granules contain vasoactive amines
- Histamine
what are mast cells
Inflammatory process
• Contain histamine and heparin
what is Agranulocytes
➢ Monocytes and macrophages make up the mononuclear phagocyte system (MPS) ➢ Monocytes ➢ Macrophages ➢ Lymphocytes ➢ Natural killer (NK) cells
what are platelets
Disc-shaped cytoplasmic fragments of megakaryocytes ➢ Essential for blood coagulation and control of bleeding ➢ Survive for 10 days