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Flashcards in Haematology Deck (26):
1

buffy coat

White cells + platelets

2

What is the blood made up of?

Red cells
White cells
Platelets
Plasma

3

Granulocytes

Neutrophils
Eosinophils
Basophils

4

Agranulocytes

Lymphocytes
Monocytes

5

Red cell function

Transport oxygen

6

White cell function

Respond to infection and inflammation

7

Platelet function

Prevents bleeding

8

What does MCV stand for?

Mean Cellular volume - size of the red cell

9

What is needed for nucleus maturity of developing red cells?

B12 and folate

10

Cause of microcytic anaemia

Iron deficiency - chronic blood loss

11

Causes of macrocytic anaemia

Vitamin B12/folate deficiency - nuclear defects

12

Causes of normocytic anaemia

Acute blood loss or anaemia of chronic disease

13

Causes of macrocytic red cells without anaemia

Alcohol excess
Liver disease
Hypothyroidism

14

Function of a blood film

To confirm the abnormalities identified by an analyser

15

Name the 5 types of leukocyte

Neutrophil
Lymphocyte
Monocyte
Eosinophil
Basophil

16

Increase in neutrophils

Stress ot steroids

17

Increase in eosinophils

Parasitic infection or hypersensitive/allergic reaction

18

Increase in basophils

Hypersensitivity reactions

19

Increase in monocytes

Chronic infections

20

Increase in lymphocytes

Viral infections e.g. glandular infections

21

Haemostasis

The arrest of bleeding and the maintenance of vascular patency

22

4 components of the haemostatic system

Formation of platelet plug
Formation of fibrin clot
Fibrinolysis
Anticoagulant defence

23

Sequence of platelet function

Adhesion - activation - secretion - aggregation

24

2 coagulation screens to know

Prothrombin time - II, V, VII, X
Activated partial thromboplastin time - II, V, VIII, IX, X, XI, XII

25

When does prothrombin time (PT) change?

Liver disease - takes longer

26

Fibrinolysis

Enzymatic breakdown of the fibrin in blood clots