Haematology Flashcards Preview

CAP Test Year 3 > Haematology > Flashcards

Flashcards in Haematology Deck (11):
1

When is it reasonable to consider a blood transfusion?

Hb < 8, especially with symptoms

2

What blood will be transfused in the following case:
A large epistaxis which has settled over the last 30 mins with conservative management. Patient light headed and nauseous. Hb 7.1

IV packed red blood cells

3

What is the mechanism of action of aspirin?

Inhibits cyclooxygenase

4

What is the mechanism of action of clopidogrel?

Antagonises adenosine diphosphate receptors on platelets

5

What is the mechanism of action of warfarin?

Inhibits vitamin K epoxide reductase, preventing carboxylation of vitamin K dependent factors

6

What are the vitamin K dependent factors?

II, VII, IX, X

7

What is rouleaux formation?

Red cells will appear stacked like a set of coins
Can be found in reactive process due to acute phase proteins or in plasma cell dyscrasias due to paraproteins

8

What is not an appropriate action in a patient on warfarin presenting with haematemesis and hypotension?

Giving fresh frozen plasma
Does not give sufficient coagulation correction

9

Diagnosis: 18 y/o male, 8 week enlarging lump in neck, night seats, axially lymphadenopathy

Hodgkin's Disease

10

Which investigation is most likely to give a definitive diagnosis of Hodgkins Disease?

Lymph node biopsy

11

Which test is used to dose heparin?

APTT