Hardy-Weinberg

Question 0

Normal allele frequency =

Mutant allele frequency =

Answer 0

p

q

Question 1

Hardy-Weinberg eqn

Answer 1

p^2 + 2pq + q^2 = 1

where p+q = 1

Question 2

proportion of affected individuals =

Answer 2

q^2

Question 3

proportion of unaffected (non-carrier) indivudials

Answer 3

p^2

Question 4

proportion of carriers (carrier frequency) =

Answer 4

2pq

Question 5

Allele frequencies in the next generation?

Answer 5

Same. Equilibrium is an assumption

Question 6

In the case of Beta-thalassemia, what is the proportion of matings that produce affected offspring?

Answer 6

(2pq)^2

…homozygous individuals with Beta-Thalassemia are assumed to not reproduce due to the severity of the disease