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Flashcards in heart and blood vessels Deck (11)
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1

3 forms of arteriosclerosis

Atherosclerosis
mockeberg medial calcific sclerosis
arteriosclerosis

2

most important form of arteriosclerosis

Atherosclerosis

3

ATH has intimal lesions called what?

ateheromas, athermatous plaques and fibrofatty plaques

4

what is the most important manifestation of
ATH

CHD

5

basic features at ATH?

raised focal lesion of the intima
soft yellow core of cholesterol
esters covered by a fibrous cap
Fatty streak appears first miscroscopically

6

components of ATH

cells: smooth muscle cells
superfiscial fibrous cap
deep fibrous cap with necrotic core of lipids and foam cells

7

complications of ATH

hemmorrhage into plaque
rupture/ulceration/erosion
superimposed thrombosis
aneurysmal dilation
fatty streak

8

fatty streak can develop into

atheroma

9

steps of development of ATH

chronic endothelial injury
adhesion of blood monocytes to endothelium
adhesion of platelets
migration of smooth muscle cells to media to intima
increased accumulation of lipid within the cell and outside

10

PT. has either benign HTN, diabetes, elderly, or benign nephrosclerosis and you see pink hyaline thickening of the walls what arteriosclerosis do they have

hyaline

11

PT. has malignant nephrosclerosis and you see a onion skin appearance on the walls on the lumen what arteriosclerosis does the pt. have

hyperplastic