Heart Failure Treatment Flashcards Preview

Pharma > Heart Failure Treatment > Flashcards

Flashcards in Heart Failure Treatment Deck (15):
0

Digoxin

Cardiac glycoside.
Inhibits nakatpase. Increases intercellular calcium, increases cardiac contractility

1

Left sided heart failure

Orthopnea, PND, Pulmonary congestion

2

Right sided heart failure

Hepatomagaly, edema, engorged neck veins

3

Digoxin side effects

Narrow therapeutic window. Causes visual changes yellow halos

4

Drugs with a narrow therapeutic index.

WALA na Cyang PaPa! VasTeD na!
Warfarin, aminoglycosides, lithium, amphotericin b, carbamazepine, Phenobarbital, phenytoin, Vancomycin, Theophylline, Digoxin

5

Digitalis toxicity

Exacerbated by hypokalemia, hypomagnesemia, and hypercalcemia.
Arrythmogenesis

6

Treatment of digitalis toxicity

Correct electrolyte imbalance
Lidocaine as antiarrhythmic
Fab fragments Digibind

7

Diuretics

Furosemide for immediate reduction of pulmonary edema,
Spirinolactone and eplerenone

8

Angiotensin antagonist

Reduce aldosterone secretion
Decrease ventricular remodeling cardioprotective

9

Beta1 selective sympathomimetic

Dobutamine and dopamine for acute heart failure

10

Beta blocker

Carvedilol, labetalol, metoprolol, reduces progression of chronic HF

11

Phosphodiesterase inhibitors

Inamrinone, milirinone,
Increases cAMP, Intrecellular calcium causes vasodilation

12

Survival in CHF

ABA! Buhay ka pa!
ACEIs
Beta blocker
Aldosterone antagonist

13

Hydralazine and isosorbide dinitrate

Shown to reduce mortality in African Americans

14

Nitroprusside, nitroglycerin

Increases afterload