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Flashcards in Heart l Deck (25)
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1

ALT > AST means...
AST elevated can mean...

LR Dz
Heart - MI

2

GGT / GGTP elevated means...

alcohol toxicity - sign of elevated glutathione activity

3

LDH elevated means....

increase in lactate --> pyruvate metabolism (anaerobic problems)
- must fractionate it if abN

4

LDH1 > LDH 2 means...

MI

5

Folate is increased in...

LR Dz, non-fasting state

6

Apo 1 is good or bad

good HDL

7

Apo B is good or bad

bad

8

Lp-a is good or bad (lipoprotein a)

bad

9

Bad SE of statin use is....

Rhabdomyolysis - muscle & jt pain, increase in LR enzymes

10

Niacin SE
what to supplement w to reduce SE

hepatoxocitiy, flushin
vit B, C

11

Fibrate will do what?

decrease TGs

12

Diuretics work on what part of the KD

nephron

13

Which diuretic is CI w sulfonamide drugs

Thiazide

14

3 classes of diuretics and %

carbonic anhydrase 67
loop 25
thiazide 8

15

Spironolactone fxn

aldosterone antag at distal tubule
K sparing

16

Which diuretic can cause hypokalemia and hyperglycemia

Furosemide - loop of henle
HCTZ - distal tubule

17

K sparing means what?
Which drugs are K sparing?

triamterene, spironolactone

18

Anti HTN drugs

BB, Ace-i, arbs, alpha-2 ag, catcholamine, CCB

19

BB ADR
should you taper?

fatigue
yes

20

what does CCB do? types?
SE?

elongate AP- longer contraction -
- dil
- zem
- pine

SE = CHF

21

K sparing Anti-HTN drug

ARBs (risk of hyperkalemia)
ACE-I

22

ACE-i C/I
SE

pregN
SE: dry cough, hyperkalemia

23

Emergency HTN Tx is?

Clonidine
alpha 2 agonist
CNS sympatholytic

24

Reserpine fxn
botanical
CI

Rauwoflia
- Tx HTN, depletes catcholamines
- peripheral anti-adrenergic
- tx high anxiety & HTN
CI in depression / parasympatho state

25

CHF - what imaging?

ECHO