HEMA LEC 2 - Cell Populations in Diff Lineages Flashcards Preview

► Med Misc 05 > HEMA LEC 2 - Cell Populations in Diff Lineages > Flashcards

Flashcards in HEMA LEC 2 - Cell Populations in Diff Lineages Deck (13):
1

granulocytic lineage
first morphologically recognizable cell

myeloblast

2

granulocytic lineage
immature cell markers myeloblast

CD34, CD38, HLA-DR, stem cell factor CD117

3

granulocytic lineage
panmyeloid markers of myeloblast

CD13, CD33

4

CD of promyelocyte of granulocytic lineage

CD15

5

granulocytic lineage
CD 16 is acquired
Density of CD13 increases

myeloid near band stage

6

monocytic lineage
Earliest immunophenotype stage – gradual increase in density of ___ (3)

CD13, CD33, CD11b antigens

7

monocytic lineage
antigens of promonocyte

CD15, CD14

8

monocytic lineage
Bright expression of ___ (2) persists throughout maturation

CD 64 and HLA-DR antigen

9

Do not express pan-hematopoietic marker CD45

ERYTHROID LINEAGE

10

earliest erythroid marker of
ERYTHROID LINEAGE

CD71

11

ERYTHROID LINEAGE
Density of this antigen increases starting from
the pronormoblast stage

CD71

12

Density of CD71 erythroid lineage is down-regulated in

reticulocytes

13

ERYTHROID LINEAGE
first appear at the basophilic
normoblast stage

Glycophorin A

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