Flashcards in Hematology Exam Deck (59)
Where are monocytes found/stored?
found in blood stream
stored in spleen
Where are macrophages?
What type of immunity are NK cells
non-specific immunity, recognize NON-self
Left shift = high number of immature WBC
What do you see with left shifts and what does it indicate?
increase segments and bands on CBC
serious infections (bacterial)
bone marrow suppressed , no production
Leukemoid Rxn is define by what lab result?
What do you have to rule out with leukocytosis of >50,000?
chronic myeloid leukemia
What is leukemoid Rxn caused by?
normal WBC count
4,400 - 11,000 cells/microL
WBC count for severe neutropenia
deficiency in O2 carrying capacity of blood from low RBC or HGB defect or defect in iron carrying capacity
% of RBC in blood
normal HGB for adult male and female
men: 13.8-18 g/dL
women: 12.1 - 15.1 g/dL
What lab results to look at in anemia?
Hypochromic, microcytic anemia caused by
HGB alpha/beta chain defect: thalassemia
heme porphyrin ring defect: porphyria
iron availability: IRON DEFICIENCY ANEMIA BIGGEST CAUSE
MCV, MCHC, MCH lab results for hypochromic, microcytic anemia
MCV: <80 fL
MCHC: <32 fL
MCH: <27 fL
Ratio of HCT to HGB
HCT always 3x HGB
(10 x HCT%) / RBC count
#1 Tx for iron deficiency
ferrous sulfate (PO) atleast 3 months (ideal = 6mon)
Most common causes of iron deficiency
Pregnancy + Lactation
Gold standard test for iron deficiency
bone marrow produces ringed sideroblast instead of healthy RBC (ring of iron deposits)
What to see on smear for sideroblastic anemia
hyperchromic, microcytic, ringed sideroblasts
Treatment for sideroblastic anemia
controlling symptoms and prevent organ damage from iron overload
Chelation therapy to remove iron
abnormal alpha, beta HGB
What to see on smear for Thalassemia
hypochromic, microcytic, target cells
Most common symptoms seen with Porphyria
cutaneous skin symptoms like photosensitivity