heme/onc

Question 1

neutrophilia

Answer 1

inc neutrophils 
acute bacterial
leukemia
inflammation
trauma

Question 2

neutropenia

Answer 2

dec neutrophils
viral infection
apalstic anemia
radiation therapy

Question 3

eosinophilla

Answer 3

Neoplasm (cancer)
Allergies
Addisons
Collagen vascular diseases (autoimmune, lupus)
Coccidiomycosis (valley fever)
Parasites

Question 4

monocytosis

Answer 4

inflammatory disorders, UC,

viral, parasitic infections, Tb

Question 5

monocytopenia

Answer 5

corticosteroids

Question 6

corticosterods

Answer 6

monocytopenia
lymphocytopenia
eosinopenia (opposite of addisons)

Question 7

dont respond to bacterial or viral infections

Answer 7

basophils and eosinophils

Question 8

thrombocytosis

Answer 8

cancer
estrogen/OCPs
polycythemia vera
postsplenectomy syndrome

Question 9

thrombocytopenia

Answer 9

Autoimmune
ITP (mc in kids)
(petechia purpura epitaxis menorrhagia)
TTP

Question 10

RBCs lifespan

Answer 10

live for 120 days then extracted by spleen

Question 11

polycythemia

Answer 11

inc RBC count (inc HgbHct) b/c
relative b/c dehydration
absolute = true increase

Question 12

polycythemia vera

Answer 12

primary: bone marrow making too much erythroid cells
tx w/ phlebotomy
secondary: inc epo w/ tissue hypoxia b/c copd
HA dizzy tinnitus blurred vision fatigue pruritus after warm shower

Question 13

microcytic anemia

Answer 13

Fe deficiency
Lead poisoning 
Anemia of chronic disease
Thalassemias
Sideroblastic anemia

Question 14

macrocytic anemia (megaloblastic)

Answer 14

folate (B9) deficiency 
B12 (cobalamin) deficiency 
copper deficiency
pernicious anemia (less B12)

Question 15

macrocytic anemia (non-megaloblastic)

Answer 15

Liver disease

etoh

Question 16

normocytic

Answer 16

Fe deficient
chronic disease aplastic anemia
borderline B12 (inc)
borderline Folate (inc homocysteine)
hemolytic anemia
sickle cell
G6PD deficient

Question 17

basophilic stipling

on smear

Answer 17

blue granules in cytoplasm RBC
thalassemia
etoh abuse
lead/metal poisoning

Question 18

target cells

on smear

Answer 18

hemoglobinopathy
thalassemia
live disease

Question 19

rouleaux formation

Answer 19

multiple myeloma

Question 20

fragmented

Answer 20

shistocytes
helmet cell
(DIC, TTP, foreign valve)

Question 21

heinz body

Answer 21

on crystal violet stain
G6PD deficient
automimmune anemia
thalassemsia

Question 22

bite cells

Answer 22

bite cut out
G6PD deficient
hemolytic anemia

Question 23

howell jolly bodies

Answer 23

sickle cell
hemolytic anemia
megaloblastic anemia
s/p (after) splenctomy

Question 24

smudge cells

Answer 24

reminants of fragile lymphocytes

CLL (chronic lymphocytic leukemia)

Question 25

blasts (immature cells) lymphoblasts myeloblasts

Answer 25

always abnormal | malignancy

Question 26

ferritin transferrin TIBC transferin saturation

Answer 26

ferritin- stored TIBC-binding capacity transferrin-bound transferin saturation-

Question 27

thalassemia

Answer 27

heinz, target, basophilic on smear