Hepatitis Serology Flashcards
(20 cards)
Diagnosis of an active Hep A virus
IgM-HAV antibody
Diagnosis of Hep B
HBs Ag (surface) HBc Ag (core)
Diagnosis of Hep C
IgG-HCV antibody
HCV RNA - shown 1-2 weeks after infection
HBs Ag for >6months
Chronic Hep B
Antigens of a person naturally infected by Hep B
HBs Ag
HBc Ag
Antibodies of a person who is vaccinated against Hep B
IgG-HBs antibody
Antigens of a person infected with Hep B that is highly infectious
HepBe Ag
HBV DNA
What antigens is found in all Hep B individuals
HBs Ag
Presence of HCV Antigen
A past or currently active infection of Hep C
Presence of HCV RNA
A currently active infection
What is the best indicator for prognosis in Hep B?
HBV DNA
Diagnosis of Type 1 Autoimmune Hep
Anti-nuclear antibody (ANA)
Anti-smooth-muscle antibody (ASMA)
Diagnosis of Type 2 Autoimmune Hep
Anti-LKM-1
Anti-LCM-1
What are the 3 antigens of Hep B
HBs Ag (surface) HBe Ag (envelope) HBc Ag (core)
Memory aid for HBs Ag
It is the bad-boy antigen, your body wants to get rid of it as it carries with it the most symptoms.
The more HBs Ag the worse your symptoms
HBe Ag
This antigen is responsible for replicating the virus in your blood.
The more HBe Ag the easier it is to transmit
Antibody in someone that has recovered or been vaccinated for Hep A
IgG-HAV antibody
Decrease in HCV RNA
Patient is recovering
Levels of HCV RNA staying the same
Patient has chronic HCV
Presence of IgG-HDV and IgM-HDV antibodies
Active infection