Describe herpesviruses
linear, dsDNA, icosahedral capsid, enveloped
Where do herpesviruses replicate?
in the nucleus
What is a gammaherpesvirus?
EBV and HHV8 (kaposi’s sarcoma)
What are three stages of herpesvirus infections?
establishment, maintenance, reactivation
Which herpesviruses are neurotropic?
HSV-1, 2 and VZV
Which herpesviruses are lymphotropic?
CMV, EBV, HHV-6,7 and KSHV
What is treatment of chickenpox?
ACV and VZV Ig with steroids
What is the cause of roseola(exanthem subitum)?
HHV-6 and 7
Which strain of herpesvirus are almost 90% of the population seropositive for?
HHV-6 and 7
What is treatment of shingles?
oral ACV and steroids