High Yield Flashcards
(26 cards)
G s-alpha
Adenylyl Cyclase
cAMP (Increased)
Beta-adrenergic (epinephrine) receptor, glucagon, serotonin, vasopressin
G i-alpha
Adenyl Cyclase & K+ Channel
cAMP (decreased) & change in membrane potential
alpha-adrenergic receptor
G olfa-alpha
Adenyl Cyclase
cAMP (increased)
odorant receptors in the nose
G q-alpha
Phospholipase C
IP3, DAG (increased)
*don’t need to know receptor
G o-alpha
Phospholipase C
IP3, DAG (increased)
acetylcholine recptor in endothelial cells
G t-alpha
cGMP phosphodiesterase
cGMP (decreased)
rhodopsin (light receptor) in rod cells
Adrenaline (Epinephrine)
Adrenal Gland
Derivative of tyrosine
Increases BP, HR, metabolism
GPCR
Cortisol (Corticosterone)
Adrenal Gland
Steroid
Affects metabolism of proteins, inflammation
Intracellular receptor (TF)
Estradiol
Ovary Steroid Induces and maintains female secondary sex Intracellular receptor (TF)
Glucagon
alpha cells of pancreas
Protein
glucose regulation
GPCR
Growth Hormone
Pituitary gland
Protein
growth and muscle mass
cytokine/tyrosine kinase-associated receptor
Insulin
beta cells of pancreas
protein
glucose regulation
RTK
Testosterone
Testis
steroid
induces and maintains male secondary sex characteristics
intracellular receptor (TF)
Thyroid hormone (T3, thyroxine)
Thyroid gland
tyrosine derivative
stimulates metabolism
intracellular receptor (TF)
Vitamin D
Kidney
Steroid
Bone metabolism
Intracellular receptor (TF)
Epidermal Growth Factor
Various cells
Protein
Stimulates epidermal and others to divide
RTK
Platelet-Derived growth factor
Various cells, including platelets
Protein
Stimulates many cells to proliferate
RTK
Nerve Growth Factor
Various innervated tissues
Protein
Promotes survival of neurons
RTK
Transforming Growth Factor-B (TGF-B)
Many cell types
Protein
Inhibits cell proliferation, stimulates ECM
Serine/threonine receptor kinase
Nitric Oxide
Nerve, endothelial, BV, testis
dissolved gas
smooth muscle relaxation, nerve cell activity
None
Acetylcholine
Nerve terminals
choline derivative
excitatory
GPCR
gamma aminobutyric acid (GABA)
Nerve terminals
Derivative of glutamic acid
inhibitory
GPCR
Which Apo activates LPL?
ApoC-II
Which Apo allows for uptake of chylomicron remnants?
ApoE
