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Flashcards in HighYield Deck (48):
1

What foods are in the Prolamin superfamily?

seed storage proteins (seeds, tree nuts, legumes - CEREALS) ; lipid transfer proteins, alpha amylase/protein inhibitors)

2

What foods are in the cupin superfamily?

7s vicillin and 11s globulins (seeds, tree nuts, legumes)

3

Which foods are in the PR10 superfamily?

Betv1: apple, pear, stone fruits, celery, soybean, peanut

4

Milk allergen name

Bos d - casein, lactalbumin

5

Egg allergen name

Gal d - vovomucoid, ovalbumin, ovotransferrin

6

Wheat allregen name

Tri a

7

Peanut allergen name

Ara h

8

Shrimp allergen name

Lit v 1 (myosin Light chain), Pen a 1 (troPomyosin)

9

Fish allergen name

Gad c 1 (parvalbumin)

10

Soy allergen name

Gly m

11

Hazelnut allergenname

Cor a 8,9

12

Apple allergen name

Mal d

13

Legume and legume reaction risk?

5%

14

Tree nut and tree nut reaction risk?

37% (12-37%) **** must know on boards

15

Fish and other fish reaction risk?

50% (30-75%)

16

Shellfish allergy and other shellfish reaction risk?

75%

17

Grain allergy and other grain reaction risk?

20%

18

Cow's milk allergy and beef reaction risk?

10%

19

Cow's milk allergy and goat's milk reaction risk?

92%

20

Cow's milk allergy and mare's milk reaction risk?

4%

21

Pollen allergy and fruits/veg reaction risk?

55%

22

Peach allergy and other Rosacea reaction risk?

55% (P3AC: peach, plum, pear, apple, cherry)

23

melon allergy and other fruits reaction risk?

92%

24

latex allergy and fruits reaction risk?

35%

25

egg allergy and chicken allergy risk?

22-32%

26

Crustacean allergy and other crustacean risk?

38% (35%)

27

crustacean allergy and mollusk risk?

14% (15%)

28

mollusk allergy and other mollusk risk

49% (50%)

29

tree nut and peanut (legume) risk

35%

30

peanut and soy allergy risk

5%

31

Almond pair with?

Almond and Hazelnut

32

Lentil pairs with?

Lentil and chickpea

33

Pecan pairs with?

Pecan and walnut

34

Hazelnut pairs with?

Hazelnut and almond

35

What is the size of a grass pollen allergen?

20-45 micrograms

36

Papain vs Pepsin

PApAin cleave Above hinge: 2 fab, 1 Fc
Pepsin cleaves below hinge: (fab)2

37

Different between Fab one Fab2

Fab can bind and not cross link; Fab2 cannot bind or crosslink
- neither can fix complement or bind to the Fc receptor on the cell surface

38

What is the difference between DNA-PK and ku?

- DNA-PK: opens up hairpins at coding ends
- ku: binds broken DNA ends and recruits DNA-PK: "Think broKU DNA ends"

39

Which cells secrete surfactant in the lung?

Type 2 alveolar cells

40

What are the TCA antidepressants?

amitriptyline, nortriptyline, imipramine

41

Effective doses for standardized pollens?

RaCe to the GDP(B)
- RW: 1000-4000 AU
- Cat: 1000-4000 BAU
- Grass: 1000-4000 BAU
- DM: 500-2000 AU
- Bermuda: 300-1500 BAU
- Venom: 100mcg single; 300 mcg mixed

42

What is the effective dose for dog allergen in AIT?

15 micrograms of Can f 1
"My dog weighs 15 lbs"

43

What is the effective dose for short ragweed allergen in AIT?

6-12 microgram of Amb a 1

44

Which HLA , cytokines, and complement regulatory proteins are placental specific?

- HLA-E, F, G
- PGE2, IL-10, Il-4 - regulatory cytokines
- CD46, DAF - prevent complement activation

45

Muscarinic Receptor functions

M1: eosinophils in COPD; found in ganglia and mast cells
M2: Inhibitory rec on parasympathetic nerves: decreased in viral infections, increased Ach
M2: primary mediator of smooth muscle contraction in human airways - increases intracellular Ca, casting bronchoconstriction
-- H1 blockers can have AntiAch effects via M3 receptor

46

Steroid drug metabolism

INCREASE LEVELS:
Cathy TROLls UP the RITunda looking to Kates Birth Control
- Clarithromycin
- troleandromyecin
- increase steroid levels
- Ritonavir (Protease Inhibitor)
- Ketoconazole
- OCP

47

Sulfa antibiotic versus antibiotic: what is the difference?

Non-antibiotic does not have the aromatic amine at the N4 position (and why there is little cross reactivity)
- Sulfa antibiotic: SO2NH2 moiety

48

Which extract has slow release of allergen?

Alum - works through the NLRP3 system