Flashcards in Histology Deck (18):
From the inside out, what is the general layout of hollow organs?
Mucosa (Epithelium, Lamina propria, muscularis mucosa), submucosa (glands), muscularis externa, Adventitia
____ epithelium line the body cavities that open to outside.
What are the two distinct epithelial regions in the nasal cavity?**
olfactory and respiratory
How does the nasal cavity modify incoming air?**
1. Concha increase filtration and surface area by increasing the number of eddies, which are circular air movement.
2. warms, moisten, filters,
3. Vestibule mucus traps particles
What kind of cells are present in the respiratory region?
PSCC, basal cells, brush cells, small granule cells, goblet cells, ciliated cells, basement membrane, lamina propria has lymphocytes, vessels, and glands
What kind of cells are present in the olfactory region?**
OC (bipolar neurons), SC (physical, metabolic support), BC (replace other cells)
Describe the lamina propria in the olfactory region and in the respiratory region?
O: bowman's glands, nerve fibers, attach to bone
R: lymphocytes, blood vessels, glands, attach to bone
Type of cell in nasopharynx
PSCC with goblet cells
Type of cell in oropharynx
stratified squamous, non-keratinized
Cell lining the larynx
PSCC with goblet cells EXCEPT over vocal folds-- stratified non-keratinized squamous
What are the layers of the trachea?
mucosa (PSCC, lamina propria, bm, lymphocytes, no muscularis), submucosa, cartilage (hyaline), adventitia
How do bronchi walls change once they are intrapulmonary?
the cartilage rings become cartilage plates. Additional muscularis mucosa appears in the muscosal layer: PSCC-- LP--BM--MM--subM--cartilage plates
Describe the layers/histology of bronchioles and terminal bronchioles from inside out
1. muscosa: mainly PSCC, some simple columnar and cuboidal, no goblets
2. Non-PSCC cells have clara cells that secrete CC16 and suface active agent
3. increast muscularis mucosa to regulate resistance to flow
4. no submucosa, goblets, or glands
What kind of cells are seen in respiratory bronchioles?
ciliated cuboidal cells and clara cells proximally, clara cells distally
What type of cells make up alveolar epithelium?
Type 1 alveolar epithelium. Thin squamous cells where gas exchange occurs
Type 2 alveolar epithelium. Thin cuboidal cells that secrete surfactant and regenerate type 2 and type 1
Describe the difference between thick and thin regions of alveoli
thick contains fibros and macs. Thin has surfactant, type 1 cells and type fused basal laminas of type 1 epi and capillary endo.
What are alveolar pores of kohn?
allows air to pass between alveoli in case of non ventilating or non perfused alveoli