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Flashcards in Histology Deck (36):
1

Location of simple squamous

endothelium and mesothelium

2

location of simple columnar

lining of small intestine

3

function of simple columnar

absorption

4

function of keratinized stratified squamous

protection on exposed surfaces

5

location of keratinized stratified squamous

epidermis

6

function of non-keratinized stratified squamous

protection of wet surfaces

7

location of non-keratinized stratified squamous

esophagus

8

location of ciliated pseudostratifed columnar

trachea

9

function of ciliated pseudostratifed columnar

cilia-mediated transport

10

location of transitional

urinary bladder

11

function of transitional

allows for dissension of bladder

12

Characteristics of surface epithelia

- cells are closely apposed
- present at free surface
- rest on basement membrane
- avascular
- form continuous sheets
- epithelial cells are 'polarized'

13

how are stratified epithelia are named

on basis of shape of cells in most superficial layer

14

male reproductive surface cells have

stereocilia

15

Locations of surface epithelia

- cover external surfaces of body
- line body cavities
- line "body tubes"
- line vascular channels

16

Appearance, location, function, and structural molecular functions of Zonula Occludens (tight junctions)

APPEARANCE
- membranes appear fused together
- jumbled mess

LOCATION
- outermost of junctional complex

FUNCTION
- prevents molecules from passing b/w cells
- occludes space b/w cells

STRUCTURAL MOLECULAR FEATURES
- network of proteins encircle cell --> seals it to membranes of adjacent cells

17

Appearance, location, function, and structural molecular functions of Zona Adherens

APPEARANCE
- nice lines that attach cells to each other

LOCATION
- middle of junctional complex

FUNCTION
- keeps epithelial cells from separating when stretched
- spreads out mechanical forces

STRUCTURAL MOLECULAR FEATURES
- proteins encircle cell --> joins it to adjacent cells
- E-cadherin binds adjacent cells which attaches to actin filaments

18

Appearance, location, function, and structural molecular functions of Macula Adherens (desmosomes)

APPERANCE
- spot-like points of attachment b/w cells

LOCATION
- innermost of junctional complex

FUNCTION
- Super strong
- help dissipate mechanical forces
- attach cells to one another

STRUCTURAL MOLECULAR FEATURES
- Desmocollins and desmoglenins attach to
intermediate filaments within cell

19

Appearance, location, function, and structural molecular functions of Gap Junctions

APPEARANCE
- several hundred connexons cluster together

LOCATION
- below desmosomes
- all along lateral surface

FUNCTION
- communicating junctions

STRUCTURAL MOLECULAR FEATURES
- connexon

20

Function and location of microvilli

FUNCTION:
- increase absorptive surface area
- core consists of parallel bundles of actin filaments
- actin filaments extend into apical cytoplasm where they interact with filament

LOCATION:
- villi in small intestines

21

Function and location of glycocalyx

- rich in digestive enzymes

LOCATION:
- intestinal epithelial cells

22

Function and location of stereocilia

FUNCTION:
- increase absorptive surface area
- very long microvilli
- have actin core

LOCATION:
- ductus epididymus - play a role in absorption
- sensory cells of the ear - play a role in signal transduction

23

cilia

- 3x larger than microvilli

- visible w/ LM

- core (axoneme) consist of 9 outer doublet microtubules + 2 single central MTs

- motile: coordinate movement to move mucous

- Location: trachea (respiratory tract)

24

Hematoxylin

- blue
- basophilic
- basic dye so likes acid components (DNA)

25

Eosin

- pink
- acidophilic
- acid dye so likes basic components (cytoplasm)

26

Masson-Lillie and Mallory Trichrome stain

- collagen = green
- cells = purple

27

Periodic Acid-Schiff

stains carbs magenta

28

pseudostratified columnar epithelium

- looks stratified, but really only 1 layer thick
- Male reproductive w/ stereo cilia
- respiratory w/ cilia and goblet cells

29

transitional epithelium

- designed for stretching
- dome shaped surface cells
- numerous actin filaments in apical cells
- found in urinary bladder

30

Basement membrane 2 layers

basal lamina and reticular lamina

31

Basal Lamina is composed of

- Type IV collagen
- proteoglycans: perlecan
- laminin

32

What makes up Zonula Occludens

Claudin & Occludin
(OCcludens)

33

What protein binds adjacent cells in zonula adherens

- E-cadherin
(adheren = cadherin)
- E-cadherin attaches to actin filaments w/in cell and spreads mechanical forces

34

What protein binds adjacent cells in Macula adherens (desmosomes)

desmogleins and desmocollins

(DESMOsomes = DESMOgleins & DESMOcollins)

35

What protein is used in gap junctions

6 connexin proteins form a cylindrical channel called a connexon

36

Immotile cilia syndrome is aka

Kartogener's syndrome