Histology of the Circulatory System Flashcards Preview

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Flashcards in Histology of the Circulatory System Deck (40)
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1

What separates the tunic intima from the tunic media?

The internal elastic lamina. It is fenestrated which allows for communication b/w the intima & media.

2

T/F The endothelium of the tunic intima of the b.v. lies on a basal lamina.

True.

3

What connects the tunica media & the tunic adventitia?

The external elastic lamina.
This allows for communication.

4

Where are the blood vessels (vaso vasorum) & nerves of blood vessels located?

Tunic Adventitia

5

How does the endothelium get its nourishment?

from the blood that flows thru its lumen

6

When things are transported across the tunic intima-->how are they transported?

Thru diffusion
OR thru gap jcns
OR thru pinocytotic vessels

7

What is the exception to the simple squamous rule of endothelium?

Simple cuboidal epithelium is found in the lymph nodes.
This allows white blood cells to exit the blood vessel into the lymph.

8

Describe the structure of the basal lamina.

It is acellular.
It is made up of collagen & glycoprotein.
The collagen is secreted from the endothelium.

9

What are some substances that the endothelium of blood vessels secretes?

Collagen
Laminin
NO (to keep blood vessel dilated)

10

What enzyme is bound to some endothelium?

ACE

11

How is the endothelium involve in blood clotting?

So...it prevents clotting unless there is trauma to the endothelium.
The endothelium has Weibel-Palade bodies.
These bodies can secrete von Willebrand factor...this helps facilitate the aggregation of platelets & clotting.

12

Aside from smooth muscle, what is found in the tunica media?

Elastin
Collagen

13

Aside from CT, vaso vasorum, & nerves...what is found in the tunica adventitia?

Fibroblasts
Collagen
Elastic Fibers

14

Explain the process of sympathetic innervation of blood vessels.

The nerves are on the tunic adventitia where they release NE. This NT travels thru the external elastic lamina fenestrae into the tunica media...it then travels to all of the layers of smooth muscle thru the gap jcns.

15

Which need a greater blood supply-->veins or arteries??

Veins. B/c the blood that flows thru their lumen is less oxygenated & has already been stripped of its nutrients.

16

What are the 3 types of arteries?

Elastic
Muscular
Arteriole

17

What type of CT do elastic arteries have in their tunic adventitia? Why is this important?

Loose CT
Important b/c if it were tight--would tear during the recoil.

18

What are some examples of elastic arteries?

Pulmonary Trunk, Aorta, Common Carotid, Subclavian, Common Iliacs

19

What are some characteristics of elastic arteries?

They have a lot of elastic lamellae in their tunica media.
They have prominent vaso vasorum
** all of their elastin allows for their recoil & their good handling of the pulsatile flow out of the ventricles.

20

Are there a lot of vaso vasorum supplying muscular arteries?

No. Less prominent & common.

21

What type of CT is in the tunica adventitia of the muscular arteries?

Dense.

22

What are some important features of the muscular arteries?

Prominent IEL & EEL
Super thick tunica media w/ gap jcns
absence of elastin lamellae

23

Do arterioles have vaso vasorum?

No.

24

What are some important characteristics of arterioles?

IEL poorly defined.
Not super thick tunica media.
Wall width equal to lumen diameter.
usu next to a venule

25

What are some important characteristics of capillaries?

The endothelium is one cell layer thick.
They have a thin wall.
Once cell can squeeze thru the lumen at a time.

26

How can you tell veins & arteries apart?

Lumen is a different color--veins usu pink
Veins are bigger with a thinner wall
Veins are collapsible
Arteries are circular & hold their shape very well

27

What are the 3 types of capillaries? Where are they found?

Continuous: brain, other places, tight jcns
Fenestrated: kidney, pancreas, endocrine glands, intestines...have holes
Sinusoidal: super duper leaky...found in spleen, liver, bone marrow

28

What are pericytes?

They are cells that are in capillaries & some other places that help with constriction.
They respond to NT or NO.
They can regenerate if damaged & become smooth muscle cells or endothelial cells.

29

What are venous valves made out of?

A single layer, extension of the endothelium.

30

T/F Arteries are more numerous than veins.

False. Veins are more numerous.

31

Where do white blood cells usu migrate?

Across small venules b/c they are pretty permeable.

32

Which has a larger tunica media-->large veins or medium veins?

Medium veins.

33

Do veins have tunica media & vaso vasorum?

yes. tunica media is less than w/ arteries. Vaso vasorum is more than w/ arteries.

34

What is found in the subendocardial CT of the heart?

Nerves
Blood vessels
Purkinje fibers

35

What are 3 differences b/w skeletal muscle & cardiac muscle?

Cardiac Muscle has
intercalated discs
branching
centrally located nuclei

36

Do lymphatic ducts have tunica intima?

Yes. they have all 3 layers.

37

How do you get fluid into the lymphatic capillaries?

Thru muscle contraction...flaps open & anchoring filaments hold them out so that you can get fluid in.

38

Where do lymphatic vessels drain?

Lymph nodes & lymphatic ducts.

39

Do lymphatic ducts have vaso vasorum?

YES & valves.

40

What is elephantiasis?

Infection that affects lymphatic drainage.
End up with awful edema...accumulation of fluid in the interstitial space.