HIV, AIDS, STDs Flashcards Preview

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Flashcards in HIV, AIDS, STDs Deck (14):
1

Clinical course of HIV

-6-8 weeks after initial exposure, some may experience vague low grade fever, fatigue, sore throat, or myalgias (seroconversion syndrome)
-latency period of no symptoms 6mo to 10 years (during this time, there is significant decline in T cells and immune function if left untreated)

2

Categories (stages of HIV)

1. no AIDS defining illness and CD4>500 or total lymphocytes> 29
2. no AIDS illness and 200

3

How to diagnose HIV

standard- ELISA for HIV antibodies
then if positive, confirm with WESTERN BLOT TESTING

4

Examples of AIDS defining illnesses

- P jiroveci (ground glass)
- Kaposi sarcoma
- burkitt lymphoma
- Candidiasis of bronchi, trachea, lungs
- Toxo in brain/CMV
- HIV encephalopathy
- recurrent pneumonoia
-recurrent salmonella
-wasting syndrome
-M avium complex
- Cocccidiodomycosis

5

When HIV is diagnosed...what to do next?

Must be reported to local health authorities, but partner notification varies

6

When HIV diagnosed, what labs to draw?

- HIV genotype to identify strains that may be resistant to therapy
- quantitative assay (viral load)
- CD4 AND CD8 every 3-6 months
- CBC, CMP, UA baseline and to monitor for complications
-Serology for toxo and CMV

7

What to also screen for when HIV diagnosed?

other STDs like syphilis, hep B and C, G/C, herpes
offer Hep A and B vaccines, PPD testing, and HPV/pap smears

8

Treatment for HIV

immediate referral to ID specialist and doctor with expertise in treating AIDS related conditions

HAART to keep viral load down

9

What prophylaxis should be done

- annual attenuated influenza vaccine and pneumococcal vaccine (before CD4

10

What preventative measure is CONTRAindicated to HIV patients and their household members/close contacts

LIVE VIRUS VACCINES

11

Stages of syphilis infection

primary - PAINLESS chancre, at site of infxn usually genitals
secondary - skin rash, neuro symptoms, eye abnormalities
tertiary - cardiac or granulomatous lesions (gummas)

12

How to dx syphilis

1st do RPR or VRDL
then confirm with FTA ABS (treponemal antibody)

13

Who should get screened for syphilis

all pregnant women to prevent congential syphilis
anyone found to have another STD or high risk

14

Treatment for syphilis

penicilin G!

doxy, ceftriaxone, tetracycline if allergy to PCN