Human behavior: BPSS and Interdependence II Flashcards Preview

Block 5 Week 1 Meg > Human behavior: BPSS and Interdependence II > Flashcards

Flashcards in Human behavior: BPSS and Interdependence II Deck (26):
1

The study of interactions between behavior, the nervous system, and the immune system

psychoneuroimmnology
**these systems reciprocally affect one another

2

What are innate defenses vs adaptive defenses?

surface barriers and internal defenses **inflammation

vs

humoral immunity and cellular immunity (B and T cells)

3

T/F: Inflammation plays a big role in chronic disease, and may be the link between the immune system, the endocrine system, and nervous system.

True

4

Is there a definitive causal link between stress and immunity?

No, but there are many correlations
**could involve mediating variables

5

T/F: Stress can delay wound healing

True
**caregivers had more poor immune function and took 9 days longer to heal a wound than controls
**wounds placed on dental students 3 days before an exam healed 40% slower

6

T/F: Pain can affect immune and endocrine function

True
**painful stressors, surgery, and anesthetic techniques

7

T/F: Use of drugs, alcohol, smoking, and nutrition can alter wound healing

True

8

T/F: Distressed patients more likely to have sleep/appetite disturbances

True
**deep sleep associated w release of GH
**partial sleep loss one night can result in increased cortisol levels the next evening

9

T/F: Patients with more fear/stress prior to surgery experienced greater pain, longer hospital stays, more post-op complications, poorer treatment adherence

True

10

T/F: Personality varaibles can affect post-surgical outcomes

True
**optimism

11

T/F: Interventions that target psychological influences can enhance surgical recovery

True
**pts taught about relaxation before surgery, had earlier discharge and required less morphine

12

(blank) emotions (depression, anxiety, anger) can intensify a variety of health threats (cardiovascular disease, Type II DM, certain cancers, etc.) through immune dysregulation.
Production of (blank) that influence these conditions can be directly stimulated by negative emotions and stressful experiences

negative; proinflammatory cytokines

13

T/F: Thus, distress-related immune dysregulation may be one core mechanism linking health risks associated with negative emotions to disease

True

14

T/F: Several well-controlled prospective studies have linked depressive symptoms with coronary heard disease (CHD)

True
**pts w depression 4.5 x greater risk of heart attack

15

T/F: Chronic depressed mood has been found to be linked to cancer risk

True

16

Depression linked with these things

osteoporosis (lower bone mineral density)
declines in muscle strength
reduced rehabilitation
less compliance w diabetes

17

T/F: Anxiety plays a role in the development of CHD and contributes to poorer prognosis after acute coronary events, including death and recurrent ischemic events

True

18

T/F: Chronic anger and hostility also negatively impact health

True
**men high in hostility >2x risk of cardiovascular mortality

19

Do psychosocial interventions affect immunity?

Yes
**taught med students about relaxation & students had higher helper T-lymphocyte % during exams
**relaxation in older adults increased NK cell activity

20

T/F: Social isolation constitutes a major risk factor for morbidity and mortality

True
**just as important as risk factors like smoking, BP, obesity

21

T/F: There is a link b/w social support and immune functioning

True
**not just amount of social support, but quality also important

22

What is the relationship between adverse childhood experiences and medical disease?

ACE score was linked w health outcomes - adverse childhood experiences have a powerful relation to adult health
**adverse childhood experiences are more common that expected!!

23

What is the relationship between ACE and ischemic heart disease?

the higher the number of adverse childhood experiences, the higher the risk of ischemic heart disease
**exposure to 4 or more 2x increased risk

24

What mediates the relationship between childhood trauma and ischemic heart disease?

psychological factors
**presence of depressed affect and anger moreso than cardiac risk factors!!

25

Number of adverse childhood events increases risk for what other problems?

obesity
smoking
injected drugs**
serious job problems

26

T/F: Much of what causes time to be lost from work is actually predetermined decades earlier by the adverse experiences of childhood.

True