hypersensitivity & immunity Flashcards
(33 cards)
define hypersensitivity
overreaction of the immune system to a substance that is normally harmless to most people
what types of hypersensitivity are mediated by antibodies
types I, II & III
what causes type IV hypersensitivity?
inappropriate action of T cells
type I hypersensitivity is also known as what?
allergy
what antibodies mediate hypersensitivity type II
IgG & IgM
why is the line between hypersensitivity type 2 and autoimmune blurred
IgG & IgM antibodies bind to exogenous & self antigen
why does the measles vaccine prevent against other diseases?
measles wipes out memory cells
what are two subtype of adaptive immunity
passive & active
what is colostrum
breast milk
what antibodies are transferred from the placenta?
IgG
what antibodies are transferred from breast milk
IgA
what is the difference between attenuated vaccine and a killed whole organism
attenuated - partial live organism
kill whole- whole organism is dead but your body thinks its not so u can produce the right immune response
why is an attenuated vaccine more effective than a killed whole organism vaccine?
atenuated vaccine stimulates a natural response
natural whole isnt goood as the vaccine makes ur body fight agaisnt the antigen urself so it doesnt have the antibodies to do so whereas atenuated produces its own antigens so ody can fight for itself in the future
what type of vaccine are tetanus & diptheria example of
toxoid vaccine
what type of vaccine are HPV & HEP B an example of
subunit vaccines
how many HPV vaccines are there
3
when would you not give a vaccine to a patient? state 2 temporary reasons & 2 permanent
temporary- illness & pregnancy
permanent- immunocompromised & allergy
what percent of people in the western world are estimated to suffer from an autoimmune disease?
5%
how many RNA strands do influenza virus have ?
8
what method of treatment is used to treat autoimmune disease?
blanket immunosuppression
what are the categories of hypersensitivity responses?
type I,II,III,IV (V)
which of the hypersensitvity responses are T cell mediated
IV
which antibody is type I hypersensitivity response reliant on, and why?
IgE, causes allegeric reactions
which antibody are type II and III hypersensitivity response reliant on?
IgG
