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Cancer and Clinical Genetics > Hypophosphatemia > Flashcards

Hypophosphatemia Flashcards

1
Q

Extrarenal causes

A

GI reduced absorption - chronic diarrhoea, insufficient intake
Increased intracellular sequestration - refeeding syndrome, leukemia/lymphoma, DKA recovery, resp alkalosis

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2
Q

Renal causes

A

CKD, 3ary hyperPTH

Renal PO4 leak

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3
Q

Drug related

Tumour related

A

Drugs - aminoglycosides, cisplatin, antacids

Tumour induced osteomalacia

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4
Q

Classification

  • mild
  • moderate
  • severe
A

Mild - 0.65-0.79mmol/L
Moderate - 0.32-0.64mmol/L
Severe - U0.32mmol/L

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5
Q

Management

A

Treat if moderate/severe
-PO4-sandoz effervescent

Excessive doses => hyperkalemia, hypocalcemia, metastatic calcification

Correct hypocalcemia first

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Cancer and Clinical Genetics (51 decks)

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