Flashcards in ID 10 Deck (50):
what causes intestinal tapeworm from taenia as opposed to cysticercosis/neurocysticercosis?
Ingestion of larvae, ingestion of eggs causes cysticercosis.
treatment for intestinal tapeworm (taenia solium)
treatment for cysticercosis/neurocysticercosis
cysticercosis --> praziquantel
neurocysticercosis --> albendazole
how do you prevent echinococcus related anaphylaxis?
Inject cyst with ethanol or hypertonic saline to kill daughter cysts before removal.
Ingestion of eggs from dog feces. Sheep are an intermediate host.
what are the trematodes?
2) clonorchis sinensis
liver + spleen enlargement + fibrosis + inflammation
what part of schisto life cycle penetrates humans?
How do you differentiate S mansoni from s haemotobium?
S mansoni = egg with lateral spine.
S haematobium = egg with terminal spine
other complication of s haematobium?
clonorchis sinensis causes
1) biliary tract inflammation --> pigmented gallstones
parasite associated with brain cysts, seizures
parasites associated with portal HTN
1) schistosoma mansoni
2) schistosoma japonicum
what are scabies?
serpiginous burrows (lines) in webspace of hands and feet.
mites that burrow into the stratum corneum and cause pruritus
where are scabies common?
children, crowded populations (jails, nursing homes)
1) permethrin cream
2) wash/dry all clothing/bedding
3) treat close contacts
terms for lice
intense pruritus + pink macule and papule in intertriginous areas
organisms transmitted by lice
1) rickettsia prowazekii
2) borrelia recurrentis
3) bartonella quintana (trench fever)
3) ivermectin lotion
4) nit combing
what is complementation?
1 of 2 viruses that infects a cell has a mutation that results in a nonfunctional protein and the non mutated virus complements the mutated one by making a functional protein that serves both viruses.
classic example of complementation
hep D (needs HBsAg, the envelope protein for HDV)
genome of virus A coated with surface proteins of virus B
nice thing about live attenuated vaccines..
don't need a booster
Only live attenuated vaccine you can give to immunocompetent HIV patients?
1) HBV (antigen = HBsAG)
2) HPV (6,11,16, and 18)
only ssDNA DNA virus?
circular DNA viruses?
only RNA virus that isn't ss?
positive sense RNA viruses?
which virus particles are infectious
1) nucleic acids of most dsDNA (except poxviruses and HBV)
2) positive sense strand ssRNA (basically mRNA)
1) naked nucleic acids of negative sense strand ssRNA and dsRNA viruses (require polymerases contained in complete virion).
DNA virus that replicates in the nucleus..
RNA virus that replicates in the nucleus
How do enveloped viruses acquire their envelopes? exception?
from plasma membrane when exiting except (herpesviruses (from nuclear membrane))
capsid rule with DNA viruses
all are icosahedral (except pox (complex)
how can pox virus replicate in the cytoplasm?
carries own DNA-dependent RNA polymerase
largest DNA virus
partially DS and circular
*has reverse transcriptase
1) febrile pharyngitis
2) acute hemorrhagic cystitis
4) conjunctivitis (pink eye)
Cervical intraepithelial neoplasia.
Potentially premalignant transformation and abnormal growth (dysplasia) of squamous cells on the surface of the cervix.
HPV serotypes associated with warts?
what are the polyomaviruses?
1) JC virus
2) BK virus
BK virus significance
transplant patients, commonly targets kidney. DS and circular
SS and linear