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Flashcards in ID 10 Deck (50):
1

what causes intestinal tapeworm from taenia as opposed to cysticercosis/neurocysticercosis?

Ingestion of larvae, ingestion of eggs causes cysticercosis.

2

treatment for intestinal tapeworm (taenia solium)

praziquantel

3

treatment for cysticercosis/neurocysticercosis

cysticercosis --> praziquantel
neurocysticercosis --> albendazole

4

how do you prevent echinococcus related anaphylaxis?

Inject cyst with ethanol or hypertonic saline to kill daughter cysts before removal.

5

Echinococcus transmission

Ingestion of eggs from dog feces. Sheep are an intermediate host.

6

trematode?

fluke

7

what are the trematodes?

1) schistosoma
2) clonorchis sinensis

8

schisto presentation

liver + spleen enlargement + fibrosis + inflammation

9

what part of schisto life cycle penetrates humans?

cercariae

10

How do you differentiate S mansoni from s haemotobium?

S mansoni = egg with lateral spine.
S haematobium = egg with terminal spine

11

other complication of s haematobium?

pulmonary HTN

12

clonorchis sinensis causes

1) biliary tract inflammation --> pigmented gallstones
2) cholangiocarcinoma

13

parasite associated with brain cysts, seizures

taenia solium

14

parasites associated with portal HTN

1) schistosoma mansoni
2) schistosoma japonicum

15

what are scabies?

mites

16

scabies presentation

serpiginous burrows (lines) in webspace of hands and feet.

17

scabies pathophys

mites that burrow into the stratum corneum and cause pruritus

18

scabies transmission

fomites

19

where are scabies common?

children, crowded populations (jails, nursing homes)

20

scabies treatment

1) permethrin cream
2) wash/dry all clothing/bedding
3) treat close contacts

21

terms for lice

pediculus humanus
phthirus pubis

22

lice presentation

intense pruritus + pink macule and papule in intertriginous areas

23

organisms transmitted by lice

1) rickettsia prowazekii
2) borrelia recurrentis
3) bartonella quintana (trench fever)

24

lice treatment

1) pyrethroids
2) malathion
3) ivermectin lotion
4) nit combing

25

what is complementation?

1 of 2 viruses that infects a cell has a mutation that results in a nonfunctional protein and the non mutated virus complements the mutated one by making a functional protein that serves both viruses.

26

classic example of complementation

hep D (needs HBsAg, the envelope protein for HDV)

27

phenotypic mixing

genome of virus A coated with surface proteins of virus B

28

nice thing about live attenuated vaccines..

don't need a booster

29

Only live attenuated vaccine you can give to immunocompetent HIV patients?

MMR

30

subunit vaccines

1) HBV (antigen = HBsAG)
2) HPV (6,11,16, and 18)

31

only ssDNA DNA virus?

Parvoiridae

32

circular DNA viruses?

1) papilloma
2) polyoma
3) hepadnavirus

33

only RNA virus that isn't ss?

Reoviridae

34

positive sense RNA viruses?

1) retrovirus
2) togavirus
3) flavivirus
4) coronavirus
5) hepevirus
6) calicivirus
7) picornavirus

35

which virus particles are infectious

infectious:
1) nucleic acids of most dsDNA (except poxviruses and HBV)
2) positive sense strand ssRNA (basically mRNA)
noninfectious:
1) naked nucleic acids of negative sense strand ssRNA and dsRNA viruses (require polymerases contained in complete virion).

36

DNA virus that replicates in the nucleus..

poxvirus

37

RNA virus that replicates in the nucleus

1) influenza
2) *retroviruses

38

How do enveloped viruses acquire their envelopes? exception?

from plasma membrane when exiting except (herpesviruses (from nuclear membrane))

39

capsid rule with DNA viruses

all are icosahedral (except pox (complex)

40

how can pox virus replicate in the cytoplasm?

carries own DNA-dependent RNA polymerase

41

largest DNA virus

poxvirus

42

milkmaid blisters

cowpox

43

hepadnavirus structure

ENVELOPED
partially DS and circular
*has reverse transcriptase

44

adenovirus causes

1) febrile pharyngitis
2) acute hemorrhagic cystitis
3) pneumonia
4) conjunctivitis (pink eye)

45

CIN?

Cervical intraepithelial neoplasia.
Potentially premalignant transformation and abnormal growth (dysplasia) of squamous cells on the surface of the cervix.

46

HPV serotypes associated with warts?

1,2,6,11

47

what are the polyomaviruses?

1) JC virus
2) BK virus

48

BK virus significance

transplant patients, commonly targets kidney. DS and circular

49

parvovirus structure

SS and linear

50

smallest DNA virus?

parvovirus