Iggy Chapter 20 RA, Lupus, systemic sclerosis Flashcards Preview

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Flashcards in Iggy Chapter 20 RA, Lupus, systemic sclerosis Deck (14):
1

RHEUMATOID ARTHRITIS description

Connective tissue disease
Destructive to joints and cartilage
Antibodies attack synovium causing it to thicken
Inflammatory

2

RA pannus formation

When synovium thickens
Vascular granulation tissue of inflammatory cells
Errodes articular cartilage and bone

3

Late RA sx

Fibrous adhesions
Bony ankyloses
Calcifications
Bone density loss
Secondary osteoporosis

4

RA onset

more common in winter

5

RA characteristics

chronic and progressive
natural remissions and exerbations

6

RA effects which ethnicity most

euro-americans

7

Causes of RA

environmental and genetic
Female reproductive hormones play a role
Stress

8

Who gets RA?

young to middle aged women

9

Early RA sx

Fatigue
Low-grade fever
Generalized weakness
Anorexia (2-3 lb loss in early stage)
Paresthesias
“migratory arthritis”

10

RA Baker’s cysts

enlarged popliteal bursae behind knee
Cause tissue compression and pain

11

RA Gel phenomenon

last 45 min – several hours .
Joints are soft and puffy (synovitis and effusions – esp. in the knees)

12

RA Vasculitis

Late sx
Organ supplied by arterial vessels become ischemic, malfunction, and fail

13

RA peripheral nerropathy

from decreased circulation
leads to foot drop and paresthesias

14

RA respiratory complications

Pleurisy
Pneumonitis
Diffuse interstistial fibrosis
Pulmonary HTN