Imaging in inflammatory disorders and infection Flashcards Preview

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Flashcards in Imaging in inflammatory disorders and infection Deck (17):
1

what does gamma radiation occur from?

radioactive decay of unstable isotopes

2

what type of energy do gamma rays produce?

high energy, high frequency

3

what are radiopharmaceuticals composed of?

radioactive element
phamaceutical element

4

what does the pharmaceutical element do?

determines which part of the body the agent travels to

5

what are some properties of an ideal isotope?

half life similar to length of examination
gamma emitter as opposed to alpha or beta
energy of gamma rays should be 50-300 keV
radionuclide should be readily available at the hospital site
easily bound to pharmaceutical component
radiopharmaceutical should be simple to prepare
radiopharmaceutical should be eliminated in a similar half-time to duration of examination

6

what is the half life of 99m technium?

6 and a half hours

7

what is used to capture an image of a patient that has been introduced to a radipharmaceutical?

gamma camera

8

what can influence image quality of a gamma camera?

radiation dose
collimator
metal objects
proximity of area of interest to the camera

9

are bone scans common?

yes

10

how would you be able to tell if a patient is of a younger age due to a bone scan?

growth plates are still visible

11

what investigation would you use to assess kidney function and drainage?

radionucleotide renogram

12

what are some features of single photon emission computed tomography (SPECT)?

CT version of nuclear medicine
gamma cameras rotate around area of interest
routinely used for brain and cardiac studies
can be applied to any site of interest in other studies

13

what 2 stages are patients investigated at during a myocardial perfusion SPECT?

rest
pharmocological stress

14

what are some features of positron emission tomography?

molecular imaging
uses radionuclides that decay by positron emission (proton --> neutron and positron)
these can be used to image biologically interesting processes
can be used for absolute quantitation but requires arterial sampling
all scanners not PET CT

15

what is the most common radiopharmaceutical used for PET investigtions?

18F-fluorodeoxy glucose

16

what is the main reason that a PET scan would be undertaken?

cancer investigations

17

what is the main risk to patients who are undergoing investigations which involve radioactivity?

main risk is ionising radiation.