Immune System I & II Flashcards Preview

Biol 351 > Immune System I & II > Flashcards

Flashcards in Immune System I & II Deck (32):
1

Innate defenses

Barriers, phagocytes, natural killer cells, inflammatory response, and fever

2

Attack cancerous cells and cells infected with viruses

NK cells

3

Defensive molecule side of specificity

antibody

4

Tag on target molecule

antigen

5

A set of similar antibodies

Immunoglobulin class

6

Two regions of an antibody molecule:

Variable region and the constant region

7

The _____ region of an antibody molecule is different in each antibody

variable

8

The ______ region of an antibody molecule is the same in each Ig class

constant

9

The ______ is the part of the antigenic molecule that binds the antibody

epitope

10

Different types of antibodies are generated by the editing of genes during the development of _____ cells

B cells

11

Glycoproteins located at the surface of T cells

T cell receptors

12

B lymphocytes (B cells) mature in the.....

Bone marrow

13

T lymphocytes (T cells) mature in the......

thymus

14

T cell receptors bind to....

antigens

15

Adaptive defence cells derived from stem cells in the bone marrow

lymphocytes

16

Have antibodies on their surface that serve as antigen receptors that have a specificity for a given antigen

B cells

17

How are B cells activated?

By antigen binding or interaction with a helper T cell

18

Clonal selection

Two B cell clones result from the activation of a single B cell with a single antigenic specificty

19

Plasma B cells function

Producing antibodies that match target antigens

20

Memory B cells function

Prolonged lifespan to remember a given antigen

21

Helper T cells function

provide link between macrophages, humoural immunity, and cell-mediated immunity; activated helper T cells in turn activate B cells and cytotoxic T cells

22

Cytotoxic T cells function

Poke holes in the plasma membrane of target cells; also have a line of memory T cells

23

Basis for acquired immunity

somatic hypermutation

24

Passive immunity

Antibodies supplied directly from the outside

25

Polyclonal antibodies

Antibodies with different epitopic specificities and bind to different epitopes of the same antigen

26

Monoclonal antibodies

Antibodies that all have the same epitopic specificity and bind to one epitope only

27

A and B antigens on RBCs are made up of?

Oligosaccharide chains attached to glycolipids and glycoproteins

28

Type A blood contains

A antigen and anti-B antibodies

29

Type B blood contains

B antigen and anti-A antibodies

30

Type AB blood contains

A and B antigens, and produces no anti-A or anti-B antibodies

31

Type O blood contains

no antigens, and produces anti-A and anti-B antigens

32

Consequences of transfusion of incompatable blood

Agglutination