Immunisation/Infection Prevention and Control Flashcards Preview

Clinical Pathology > Immunisation/Infection Prevention and Control > Flashcards

Flashcards in Immunisation/Infection Prevention and Control Deck (19):
1

Passive immunity

E.g. mother to unborn child. Maternal antibodies can be protective for up to 1 r against illnesses to which the mother is immune.

2

Active Immunity

Long lasting immunity produced by the immune system in response to antigens (either from natural infection or vaccination) 'immunological memory'

3

Live vaccines- active immunity

MMR, BCG, Yellow fever, varicella

4

Inactivated organisms- active immunity

Pertusisis, typhoid, IPV (inactivated polio vaccine)

5

Components of organisms-active immunity

Influenza, pneumococcal

6

Inactivated toxins

Diptheria, tetanus

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Advantages of active immunity

Long-lasting, strong, local and systemic immunity

8

Disadvantages of active immunity

Potential to revert to virulence

9

Passive immunity

Vertical transmission from mother-foetus and breastfeeding

10

Give some examples of passive immunity

HNIG (human normal immunoglobulin) Botulism, hep B, rabies

11

Advantages of passive immunity

Stable-unable to cause infection

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Disadvantages of passive immunity

Need several doses, local reactions common, adjuvant needed to increase the body's immune responses, shorter lasting imunity

13

Describe the cycle of infection

Pathogenic organism>reservoir>exit>trasmission>entry>susceptible host

14

Decontamination

Umbrella term for sterilization.disenfection,antisepsis Removing organisms/cntaminants e.g. environmental hydrogen peroxide decontamination

15

Asepsis

the absense of bacteria, viruses or other microorganisms e.g. MRSA decolonisation. Antibiotic prophylaxis

16

Sterilization

Complete killing or removal of all types of microorganisms e.g. heat, chemical or radiation

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Disinfection

Removal or destruction of sufficient numbers of potentially harmful microorganisms

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Antisepsis

Disenfection applied to damaged skin or living tissues

19

Difference between disinfection and sterilization

Disenfection- removing all pathogenic organisms with the exception of bacterial endospores
Sterilization-removing pathogenic organisms and endospores