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Flashcards in Immunisations Deck (46):
1

when do people get vaccinations (4)

childhood
elderly
before travel
occupational groups (eg healthcare)

2

which cells are involved in immunological memory and hence immunisation process (3)

memory B cells
memory T cells
long lived plasma cells

3

which antibody is the one that responds much quicker on secondary exposure of an antigen

IgG antibody

4

where are B cells made

bone marrow

('B' cells = 'B'one marrow)

5

what do B cells produce

antibodies

('B' cells = anti'B'odies)

6

what is the function of T cells

orchestrate the immune response - bind to other cells, send out signals

7

what is a live attenuated vaccine

exposure to less virulent version of the same organism

8

what is an inactive vaccine

exposure to inactivated ('killed' or not) pathogen

9

which type of vaccines always need a booster immunisation

inactive vaccines

10

what type of vaccine is diphtheria

inactive toxoid

11

what type of vaccine is hep B

inactive subunit

12

what type of vaccine is influenzae

inactive subunit

13

what type of vaccine is tetanus

inactive toxoid

14

what type of vaccine is pertussis

inactive subunit

15

what type of vaccines are used for pneumococcus, MenC and hep B

inactive conjugate vaccine

16

what do you add in a conjugate vaccine

protein

17

why do you add a protein to a vaccine in conjugate vaccines

to make the vaccine more immunogenic

18

if a vaccine has a peptide/protein adjuvant, what is it known as

conjugate vaccine

19

by making a vaccine more 'immunogenic' what does an adjuvant actually do?

promotes inflammation

20

what is a live attenuated vaccine

a less virulent version of the same organism

21

what type of virus are MMR, varicella, zoster and polio examples of

live attenuated vaccine

22

which 2 groups of people are live vaccines contraindicated in

pregnant
immunosuppressed

23

example of passive immunity (3)

blood donors
mother to child
pooled immunoglobulin

24

what is pooled immunoglobulin

when you transfer blood with a high Ig to someone with a low Ig

25

what type of immunoglobulin is transferred via breast milk

IgA

26

what type of immunoglobulin is transferred via placenta

IgG

27

what is it called when the unvaccinated people in a population are protected bc the rest of the population are vaccinated

herd immunity

28

what is the significance of egg allergy and vaccinations

vaccines are contraindicated

29

which childhood vaccine is given PO (the rest are IV)

rotarix

30

which vaccine triplet is given at age 2, 3 and 4 months

what are they for

DtaP/IPV/Hib

diphtheria, tetanus, pertussis, polio, haem influenza B

31

when is menB vaccine given for meningococcal B

2 and 4 months

32

when is PCV vaccine given for pneumococcal disease

2 and 4 months

33

what is PCV for

pneumococcal disease

34

which vaccination is given at 2 and 3 months

rotarix PO for rotavirus

35

which vaccination is for meningococcal B

menB

36

at which age do you give menC instead of menB

3 months

37

at which age (2, 3 or 4 months) do you not get a rotarix PO vaccination

4 months

38

what are the preschool boosters

what are they for

MMR
DtaP/IPV

measles, mumps, rubella
diphtheria, tetanus, pertussis, polio

39

what vaccine can be given annually for applicable kids (and adults)

flu

40

which vaccines are given at 1 year (5)

MMR
PCV
Hib
menC
menB

41

what is MMR vaccine for

measles, mumps, rubella

42

what is Hib vaccine for

haem influenza B (bc this is common in kids)

43

which vaccines are given to girls aged 11-13 twice

HPV

44

which meningococcal viruses are vaccinated against aged 13/14

ACWY (menACWY vaccine)

45

which condition can be vaccinated against by either a live vaccine or a inactivated vaccine

polio

46

which type of vaccine (live attenuated or inactive) is preferred in developed world countries for polio prophylaxis (more expensive but better)

inactivated