Flashcards in Immuno Midterm 1 Deck (20):
second child, miscarriage: pathophysiologic mechanism?
Fetal anemia caused by preformed maternal IgG to fetus' blood type
unilateral ptosis, ispilateral extraocular muscle weakness, edrophonium test: pos; what is HSR?
Type II (graves DZ)
Ankylosing spondylitis, Reiter syndrome, acute anterior uveitis positive for HLA:
hyperthyroidism (graves dz) associated with HLA:
psoriasis vulgaris is associated with HLA:
HLA associated with rheumatoid arthritis and DM type 1
HLA associated with Goodpasture syndrome, MS, SLE
recurrent pneumococcal pnuemonia, healthy until 6 months, recurrent ear infections, abscesses; underlying condition?
Mutation in tyrosine kinase (BTK gene); Bruton's agammaglobulinemia
SLE, blood in urine; what autoantibody associated with severity of renal dz
autoantibody found in drug induced lupus
Anti-Jo-1 antibody associated with?
antibody associated with lupus anticoagulant
biliary cirrhosis is associate with what antibody
recurrent pneumonia, severe persistant diarrhea, elevated IgM: analysis of peripheral leukocytes show what?
an absent ligand (CD40L) that is important for T-cell activation and induction of class switching in B-cells
HX: listeria pneumoniae, ecoli UTI, blood culture: S. aureus: what assay would be abnormal?
DHR assay (decrease in green fluorescence) BC chronic granulomatous dz
recurrent nosebleeds, multiple URI and ear infections, dry scaly rash: DDX?
Wiskott Aldrich syndrome
rash from belly piercing 3 days ago what HSR?
IV (delayed response, cell mediated)
Raynauds, telangiectasia, erosive polyarthritis, proteinuria, membranous glomerulonephritis, POSITIVE U1-RNP: DDX?
Mixed connective tissue disorder
URI, nasal crusting, epitaxis, elevated Cr, what antibody is associated
c-ANCA (granulomatosis with polyangitis)