Immunodeficiency OME Flashcards Preview

Pediatrics Board Review > Immunodeficiency OME > Flashcards

Flashcards in Immunodeficiency OME Deck (19):
1

brutons

X-linked gammaglobulinemia

no gammaglobulins - B cell deficient

all Ig levels low

2

tx of brutons

give Ig monthly

3

IgA deficient

IgA - protect mucosa

repeat GI and respiratory tract

4

anaphylactic rxn to blood transfusion

think IgA deficiency

5

hyper IgM

only fight infxn with IgM

tx - nothing - have IgM for immunity

6

digeorge

dysfunction of third pharyngeal pouch
-T cell disease

7

wide eye, low ears, small face, absent thymus

digeorge

8

mitogen stimulation assay

decreased in digeorge

9

thymic transplant

cures digeorge

10

Ca levels

watch in digeorge

11

abx prophlaxis with digeorge

PCP - bactrim/dapsone

12

wiskott aldrich

X-linked
-recurrent infxn, thrombocytopenia, eczema

diagnosis - elevation of IgG and IgM

13

tx of wiskott aldrich

bone marrow transplant

14

ataxia telangiectia

leukemia
lymphoma
DNA repair

15

SCID

no B or T cells
-mega-AIDS - PCP and MAC

tx - isolation - bubble baby

16

MAC prophylaxis

azithromycin

17

chronic granulomatous disease

dysfxn of macrophages
-no resp burst

get staph infections of skin

18

diagnosis of chronic granulomatous disease

nitro blue test

19

chediak higashi

giant granules PMNs