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Flashcards in Immunology Deck (39):
1

Plasma proteins generate a ________ pressure and this is used to _____ the fluid in the blood stream

colloid osmotic pressure, keep

2

normal differential blood count is ____ white blood cells and _____ red blood cells

75% and 25%

3

Thrombopoietin is released from the

liver

4

Red blood cells come from _____ then ____ and then its an ________

eyrythroblast, reticulocyte and erythrocyte

5

Liver stores excess iron as

ferritin

6

____ converts hemoglobin to bilirubin

spleen

7

liver metabolizes bilirubin and excretes it as

bile

8

What are the causes of Anemia

low production of red blood cells or high removal of red blood cells

9

Polycythemia is when

too high hematocrit production, high viscosity and oxygen isnèt having enough time to be released to the tissues

10

Macrophages eat pathogens and then present antigen receptors onto the MHC __

2

11

NK cells kill cells that do not have MHC ____

1

12

MHC 1 is a marker of a _____

self cell

13

T-Helper cells bind to MHC ___ and antigen of macrophages, dendritic cells and B cells

2

14

Antimicrobial proteins include:

interferons alpha and beta and complement

15

Complement proteins cause

lysis (MAC), opsonins, release cytokines, cause inflmmation

16

The classical pathway start at ___ and need antibodies _____

C1, IgG and IgM

17

The lectin pathway starts on _____ with protein____ with _____ on the pathogen and does not require _____

polysaccharide cell wayy, C4 MBL antibodies

18

The alternative pathway starts at ___ on the ___ surface and C3 convertase is cleaved by factor ___ and then ____

C3b, microbial, B, D

19

All three pathways meet at ___

C3b

20

C3b activates

opsonisation

21

C3a, C5a activates

inflammation

22

C5b-C9 activates

MAC

23

In a secondary immune response you are going to have ___ response and ___ antibodies and the response is going to ____ _______.

faster, antibodies, last longer

24

IgG is the _____ and can be transferred across the _____

most common, placenta

25

IgM is the first to be secreted in response to a ______ and cause antigen ___ and _____

anew pathogen, clumpin, complement

26

IgA is present in ___, ____ and ______

tears, saliva and breast milk

27

IgE fights _____ and attaches to ____ to release _______

parasites, mast cells, histamine

28

IgD on B cells with ____

IgM

29

Blood Type A has A antigen surface and anti B antibodies and takes blood from ___ and aggulates with ____ and ___

A and O, B Antigen, anti-A antibodies

30

Blood Type B has B antigen surface and anti A antibodies and takes blood from _____ and aggulates with _____ and ______

B and O, anti B antibodies and a antigen

31

Blood type AB has A & B surface antigens and aggulates with

NO ONE

32

Blood type O has anti A & B antigens and aggulates with _____

all blood types, and can only take from O

33

People who are Rh- _____ have anti-D antibodies

do not

34

Being Rh+ is _____ and they have _______

dominate, anti-D antibodies

35

Hemophilia A is a lack of factor

8 - so blood clotting is hard to do

36

Hemophilia B is a lack of factor

9

37

THe classical, lectin and alternative pathways all meet at

C3 convertase

38

The Intrinsic Pathway and the Extrinsic pathway all meet at the

common pathway

39

The common pathway starts at factor

10