Immunology & the eye Flashcards Preview

AY Ophthalmology > Immunology & the eye > Flashcards

Flashcards in Immunology & the eye Deck (14):
1

What are the innate parts of the eyes immune system?

Blink reflex
Tears

2

What is contained within tears?

Lysozyme
Complement
Tear ipids
secretory IgA

3

What is the only part of the eye with lymphatic drainage?

Conjunctiva

4

What cells within the conjunctiva acts as antigen presenting cells?

Dendritic cells

5

What is immune privelege?

Certain sites of the human body are able to tolerate the introduction of anigens without elicitng an inflammatory immune response

6

What is sympathetic ophthalmia?

Rare granulomatous uveitis due to trauma or surgery

7

Does sympathetic ophthalmia affect one or both eyes?

Both (exciting eye & sympathising eye)

8

Which eye conditions are type I hypersensitivity reactions?

Acute allergic conjunctivitis

9

What is chemosis?

Oedema of conjunctiva

10

Which cells are responsible for direct cell killing in type II hypersensitivity reactions?

Macrophages/NK cells
Complements (MAC)

11

Example of eye condition with type II hypersensitivity reaction

Ocular cicatricial pemphigoid

12

Presentation of ocular cicatricial pemphigoid?

Blistering lesions around the eyelids and on surface of eye

13

Example of eye condition involving type II hypersensitivity reaction?

Autoimmune corneal melting

14

Example of eye condition caused by type IV hypersensitivity

Corneal graft rejection (vascularisation leads to rejection)