ImmunoSero Part 1

Question 1

involved in t-cell activation

Answer 1

CD2 thymocytes

Question 2

assoc w/ t-c Ag receptor

Answer 2

cd3 thymoc

Question 3

coreceptor for mhc class II: target receptor for HIV

Answer 3

cd4 helper tcel

Question 4

modualtes t and b cell receptor signals

Answer 4

cd5 thymocytes

Question 5

corecep for mhc class I

Answer 5

cd8 cytotoxic tcells

Question 6

protease: marker for pre-b calla

Answer 6

cd10 b and t cell precursors

Question 7

mediates adcc and phagocytosis

Answer 7

cd16 nk cells

Question 8

assoc with regulation of b cell dvt

Answer 8

cd19 b cells

Question 9

part of bcell coreceptor: also the receptor for ebv

Answer 9

cd21 b cells

Question 10

regulates IgE synth

Answer 10

cd23 b cells

Question 11

receptor of IL-2

Answer 11

cd25 activated b and t ce

Question 12

essential in t and b cell activation

Answer 12

cd45r hematopoietic cells

Question 13

not known NK cells

Answer 13

cd56

Question 14

Ag independent phase

Answer 14

proB ce

Question 15

corecep that helps regulate b ce dvt and actv

Answer 15

cd19

Question 16

pro b cells CD

Answer 16

cd19 40 45r tdt rag1 rag2

Question 17

membrane glycop in hematopoi ce

Answer 17

cd45r

Question 18

mu chains in the cytoplasm

Answer 18

pre B ce

Question 19

has surface igm monomer

Answer 19

immature b ce;;

Question 20

immature b cell cd

Answer 20

cd21 for EBV

Question 21

receive signal to halt dvt = apoptosis

Answer 21

immature b cell

Question 22

in the spleen immature b cells dvlp into mature cells known as

Answer 22

marginal zone b cells (mature b cell)

Question 23

Ig in mature b cell

Answer 23

M and D

Question 24

antigen-dependent phase of b ce dvt

Answer 24

mature b cell

Question 25

occurs in primary follicle of secondary lymphoid organs

Answer 25

activated b cell

Question 26

receptor for IL2 (enhances prolif)

Answer 26

cd25

Question 27

lymphocyte capping

Answer 27

act b cell

Question 28

no surface ig but many cyto ig

Answer 28

plasma cell

Question 29

ab prod

Answer 29

plasma cells

Question 30

plasma cell location

Answer 30

germinal center in the periph lymphoid organs

Question 31

cartwheel appearance

Answer 31

plasma cells

Question 32

b cell diff stages

Answer 32

``` pro b pre b immature b mature b activated b plasma ce ```

Question 33

stages of t cell diff

Answer 33

double neg thymocytes double pos thymo mature t c activated t c

Question 34

t cell surface ag

Answer 34

cd2 3 5 4 8

Question 35

b cell surfaca ag

Answer 35

cd19 20 21 mhc class II

Question 36

end products T cell - b cell -

Answer 36

t - cytokines | b- Ab

Question 37

location Spleen - T B Lymph node

Answer 37

Spleen T - Periarteriolar lymphoid sheath B Primary follicles Lymph nodes T - paracortex B - cortex

Question 38

azurophilic granules LGLymph

Answer 38

NK cells

Question 39

NK surface ag

Answer 39

cd16 cd56

Question 40

Subs capable of triggering an adaptive immune response

Answer 40

immunogen

Question 41

Carrier = | hapten =

Answer 41

incr MW, protein, immunogenic | decr MW, non prot, antigenic

Question 42

Traits of immunogen

Answer 42

macromolecular size - incr MW incr immune resp chem compo and complexity - incr complex incr IR foreigness - incr diff, incr IR dosage and route - incr dose, incr IR

Question 43

linked to genetic capability to mount an IR of an indiv

Answer 43

MHC

Question 44

genes coding for mhc are found in

Answer 44

short arm of chromos 6

Question 45

``` genetic loci * chain structure * cell distrb * presents ag to class I class II Class III ```

Answer 45

I - hla ABC * a-chain, b2micr * all nucle cel * cd8 II - hla DP, DQ, DR * a b chain * b ce and APCs * cd4 III - C2, C4, factor B, TNF