Inf&Imm_H15 (D6) Flashcards

(10 cards)

1
Q

Myasthenia gravis, orgaanspecifiek?

A

Half en half, spieren => neuromusculaire junctie

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2
Q

Myasthenia gravis, type overgevoeligheid

A

Type II

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3
Q

Myasthenia gravis, genetische voorbeschiktheid

A

HLA-DR3

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4
Q

Myasthenia gravis, ontstaansmechanisme

A

IgG-antilichamen binden aan de ACh-receptor in skeletspieren.

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5
Q

Myasthenia gravis, voorbeeld van

A

blokkerende auto-antilichamen

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6
Q

graves disease, voorbeeld van

A

stimulerende auto-antilichamen

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7
Q

Graves disease, type overgevoeligheid

A

Type II

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8
Q

Graves disease, orgaanspecifiek

A

ja, schildklier

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9
Q

Graves disease, ontstaansmechanisme

A
  • auto-antilichaam bindt aan TSH-receptor op schildkliercellen (anti-TSH-receptorantilichaam bootst het effect van het echte hormoon na)
  • schildklier wordt constant gestimuleerd
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10
Q

Graves disease, ziektebeeld

A
  • hyperthyreoïdie
  • exophthalmus (uitpuilende ogen)
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