Infectious Mononucleosis

Question 1

What is infectious mononucleosis?

Answer 1

Infection caused by Epstein Barr virus spread through saliva

Question 2

Features of infectious mononucleosis?

Answer 2

Fever
Sore throat
Fatigue
Trasient macular
Neck lymphadenopathy
Tonsillar enlargement
Splenomegaly

Question 3

What are the antibodies produced for infectious mononucleosis?

Answer 3

Heterophile antibodies

Question 4

What are the investigations for infectious mononucleosis?

Answer 4

FBC shows high lymphocytes
Monospot test or Paul Bunnell test for heterophile antibodies

IgM and IgG antibody test. IgM suggests acute infection, IgG suggests immunity

Question 5

Management of infectious mononucleosis?

Answer 5

Self limiting - resolves in 2-3 weeks, causes fatigue for few months

Avoid contact sports

Don’t drink alcohol

Question 6

Which cancer is associated with EBV?

Answer 6

Burkitt’s lymphoma