Flashcards in Inflammation #4 (Murnane) Deck (19):
humoral immunity (antibody mediated)
cellular immunity (cell mediated)
mobilize adaptive defense AND provoke an immune response
T/F Most complex antigens ARE NOT found in the body (non self)
T/F Antigen presenting cells RESPOND to SPECIFIC antigens
FALSE; DO NOT
primary lymphoid organs (2)
-red bone marrow= b cells
-thymus= t cells
proteins secreted by plasma cells
What region of the antibody is VARIABLE?
What region of the antibody determines the CLASS?
Fc or constant region
T/F Antibodies DESTROY antigens
FALSE; they form complexes instead to inactivate the antigen
What are the defensive mechanisms used by antibodies? (2)
-neutralization and agglutination (clumping)
-precipitation and complement fixation
T/F B cells can switch antibody classes, BUT retain antigen specificity
(isotope switching) First they are IgM, then change to IgG (almost all secondary responses are IgG)
T/F T cells (CD4) activate B cells
Antibodies cause _____ and _____ hypersensitivities
immediate AND subacute
T cells cause ______ hypersensitivity
What do you use to treat anaphylactic shock?
Epi (alpha 1) and steroids
Which pathway attracts neutrophils to the site of inflammation?
T/F Haptens are immunogenic
FALSE: only when they are attached to body proteins and combination is marked foreign