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Flashcards in inflammation Deck (5)
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1

The Innate immune system eliminates microbes mainly by inducing ________________ and by antiviral defense mechanisms

The Innate immune system eliminates microbes mainly by inducing acute inflammatory response and by antiviral defense mechanisms

2

Inflammation is a _________________of host defense to sites of infection and tissue damage.

Inflammation is a tissue reaction that delivers mediators of host defense to sites of infection and tissue damage.

3

Microbes enter the _____________ tissue, ___, ______ and other cells recognize the microbe and respond by producing cytokines:
______
Act on the _____________ of venules near the site of infection.

Microbes enter the subepithelial tissue, DC, MA and other cells recognize the microbe and respond by producing cytokines:

TNF, IL-1
Act on the endothelium of venules near the site of infection.

4

Within the blood: _________, neutrophils, inflammatory mediator (complement protein)

Within the blood: monocytes, neutrophils, inflammatory mediator (complement protein)

5

For example, bacteria infiltrate the body. It express PAMP on surface. PAMP recognize by mast cell. Once mast cell recognize -> secrete histamine -> vessel dilation, increase vascular permeability -> increase blood flow, more immune cells come to site of infection

For example, bacteria infiltrate the body. It express PAMP on surface. PAMP recognize by mast cell. Once mast cell recognize -> secrete histamine -> vessel dilation, increase vascular permeability -> increase blood flow, more immune cells come to site of infection