Inflammation & Healing Ch. 1 Flashcards Preview

Pathophysiology > Inflammation & Healing Ch. 1 > Flashcards

Flashcards in Inflammation & Healing Ch. 1 Deck (23):
1

4 Cardinal Signs of Inflammation

Redness, Warmth, Pain, & Swelling. 5th is Loss of Function.

2

Nonspecific Defenses

Mechanical Barriers 1st Line of Defense.
(Skin, Mucous, and Secretions)
Phagocytosis and Inflammation 2nd Line of Defense.
(Neutrophils and Macrophages)

3

Anorexia

Decreased Appetite

4

Pyrexia

Fever

5

Specific Defenses

Immune System 3rd Line of Defense. (Antibodies & Lymphocytes)

6

Leukocytosis

Increased WBC Count.

7

High Erythrocyte Sedimentation Rate (ESR)

How fast RBC's settle in a sample.

8

Increased Serum Levels of Cell Enzymes

Released by necrotic cells.

9

Infection

Easier for pathogens to enter damaged tissue.

10

Ulcers

Cell necrosis and lack of cell regeneration cause erosions of tissue.

11

Perforation

Erosion through a tissue wall.

12

Skeletal Muscle Spasms

May be initiated by inflammation resulting from sprains, tendinitis, and fractures.

13

Local Complications

Decreased ROM around a swollen joint.

14

Resolution

With minimal tissue damage.

15

Regeneration

Occurs when damaged cells are capable of mitosis.

16

Replacement by Connective Tissue

With extensive damage or when cells are not capable of mitosis.

17

Contracture

Fixation and deformity at a joint.

18

Stenosis

Shortening or narrowing.

19

Causes vasoconstriction, decrease pain and edema, and usually in first 48-72 hours after injury.

Cold

20

Chronic problems, rheumatoid arthritis (improved circulation).

Heat

21

RICE

Rest, ice, compression, elevation.

22

Decreases prostaglandin synthesis at site of inflammation, and decreases pain and fever.

Aspirin

23

Benefits of what medication are decrease capillary permeability, decrease leukocyte # and mast cells, and block immune response?

Glucocorticoids