Flashcards in Inflammation & Healing Ch. 1 Deck (23)
4 Cardinal Signs of Inflammation
Redness, Warmth, Pain, & Swelling. 5th is Loss of Function.
Mechanical Barriers 1st Line of Defense.
(Skin, Mucous, and Secretions)
Phagocytosis and Inflammation 2nd Line of Defense.
(Neutrophils and Macrophages)
Immune System 3rd Line of Defense. (Antibodies & Lymphocytes)
Increased WBC Count.
High Erythrocyte Sedimentation Rate (ESR)
How fast RBC's settle in a sample.
Increased Serum Levels of Cell Enzymes
Released by necrotic cells.
Easier for pathogens to enter damaged tissue.
Cell necrosis and lack of cell regeneration cause erosions of tissue.
Erosion through a tissue wall.
Skeletal Muscle Spasms
May be initiated by inflammation resulting from sprains, tendinitis, and fractures.
Decreased ROM around a swollen joint.
With minimal tissue damage.
Occurs when damaged cells are capable of mitosis.
Replacement by Connective Tissue
With extensive damage or when cells are not capable of mitosis.
Fixation and deformity at a joint.
Shortening or narrowing.
Causes vasoconstriction, decrease pain and edema, and usually in first 48-72 hours after injury.
Chronic problems, rheumatoid arthritis (improved circulation).
Rest, ice, compression, elevation.
Decreases prostaglandin synthesis at site of inflammation, and decreases pain and fever.